This article aims to discuss left behind places in Brazil in the early 21st century. We conceptually debate the left behind places’ approach in dialogue with other contemporary theoretical perspectives. To evaluate regional inequalities in Brazil, we used the coefficient of variation, calculated at two different scales from 2002 to 2019 for GDP per capita, also considering social indicators. The results indicated a slow decline in regional inequalities. We debate the role of recently implemented public policies in this process, as well as the potentiality of these policies to identify left behind places and deal with them.