Presented paper deals with the issues of regional development and regional disparities in Slovakia in the years 2001-2014. Levelling respectively increase of regional disparities was evaluated through a set of 13 socioeconomic indicators (gross birth rate, average monthly wage, monthly labour costs per employee, employment rate, unemployment rate, net monthly income and expenses per capita, completed dwellings, creation of GDP, labour productivity per employee in industry and construction, number of organizations focused on generating profit and number of freelancers) which were used in the territorial units at the level of self-governing regions of the Slovak Republic (NUTS III level). In terms of the evaluation and comparison of regional disparities were used the Gini coefficient and the coefficient of variation for mutual comparison and validation of divergent or convergent tendencies of regional disparities in Slovakia.