Regional pulmonary oxygen saturations immediately after birth

Kersin, Sinem Gülcan; Yasa, Beril; Çetınkaya, Merih; Ilgın, Can; Özek, Eren; Bilgen, Hülya

doi:10.1016/j.earlhumdev.2022.105552

Cited by 4 publications

(21 citation statements)

References 26 publications

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“…The mean of pRSO 2 apex and pRSO 2 lateral were 75.3% and 77.8% in the TTN group at the end of the first hour, and these findings were very similar to the levels of a newborn who were in the transition period (3rd minute of life). 10 These data suggest that pulmonary NIRS levels in a newborn with TTN may not increase and reach a steady state within the first few hours after birth.…”

Section: Discussionmentioning

confidence: 70%

“…), [7][8][9] it can also be used in partially air-filled organs such as the neonatal lung. 10,11 In the literature for the first time, Yang et al 11 reported that pulmonary NIRS could be applied to premature infants. They found a positive linear correlation between pRSO 2 and arterial blood gas analysis values (PaO 2 and SaO 2 ) in preterm infants.…”

Section: Discussionmentioning

confidence: 99%

“…They suggested that the median pRSO 2 apex and pRSO 2 basal increased to 85% (66%-95%) and 84% (55%-95%), respectively, at 5 min of life, and the postnatal increase reached a steady-state around 9 min of life in healthy infants who were born above 35 weeks of gestation. 10 In the present study, the first pulmonary NIRS measurements of the newborns were performed at the end of the first hour of NICU admission to exclude the negative impact of the transition period. The mean of pRSO 2 apex and pRSO 2 lateral were 75.3% and 77.8% in the TTN group at the end of the first hour, and these findings were very similar to the levels of a newborn who were in the transition period (3rd minute of life).…”

Section: Discussionmentioning

confidence: 99%

“…14,20,21 Studies on pulmonary NIRS in the neonatal period are very recent and highly limited. 10,11 The strength of our study is that it is one of the pioneering studies on using pulmonary NIRS in the neonatal period. There are some limitations in this study, such as the small sample size, the lack of a group of healthy infants without RD, and the failure to record "fractionated tissue oxygenation" values.…”

Section: Discussionmentioning

confidence: 99%

“…[7][8][9] Pulmonary RSO 2 (pRSO 2 ) studies are extremely limited in neonatology. 10,11 The study aimed to determine the role of pRSO 2 values in the early distinction of NP from TTN.…”

mentioning

confidence: 99%

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The diagnostic value of pulmonary near‐infrared spectroscopy in the early distinction of neonatal pneumonia from transient tachypnea of the newborn

Ozdemir,

Alan,

Aliefendioglu

2023

Pediatric Pulmonology

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AimPulmonary near‐infrared spectroscopy (NIRS) is a new and promising tool for diagnosis of neonatal respiratory diseases (RD). The study aimed to determine the role of pulmonary regional oxygen saturation (pRSO2) values obtained by NIRS in the early distinction of neonatal pneumonia (NP) from transient tachypnea of the newborn (TTN).MethodsThis prospective, observational, double‐blind study was conducted in neonatal intensive care unit (NICU) between 2020 and 2021. Late preterm and term newborns hospitalized in the NICU due to the diagnosis of TTN and NP were included. Cerebral RSO2 and pRSO2 values were measured during the 1st, 24th, 48th, and 72nd hours of hospitalization, using NIRS.ResultsOf the eligible 40 infants, 65% (n: 26) were diagnosed as TTN and 35% (n: 16) as NP. The pRSO2 values were significantly higher in the TTN group than the NP group for both apexes (75.3 ± 8.7 vs. 69 ± 5.4, p: .018, respectively) and lateral lung (77.8 ± 6 vs. 72.7 ± 6.2, p: .016, respectively) in the 1st hour of hospitalization. There were significant differences in pRSO2apex and pRSO2lateral values between the 1st and 24th hours of hospitalization and the 24th and 48th hours in the NP group (p2: .001 for both). The optimal pRSO2apex cut‐off value was >72% to predict the diagnosis of NP with a sensitivity of 78.6% and a specificity of 69.2%.ConclusionPulmonary NIRS may be considered as a feasible and promising diagnostic tool in late preterm and term infants with RD. It may also be helpful for the early differentiation of NP from TTN and the courses of these diseases.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…[7][8][9] Pulmonary RSO 2 (pRSO 2 ) studies are extremely limited in neonatology. 10,11 The study aimed to determine the role of pRSO 2 values in the early distinction of NP from TTN.…”

mentioning

confidence: 99%

See 3 more Smart Citations

The diagnostic value of pulmonary near‐infrared spectroscopy in the early distinction of neonatal pneumonia from transient tachypnea of the newborn

Ozdemir,

Alan,

Aliefendioglu

2023

Pediatric Pulmonology

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Regional pulmonary oxygen saturations in late preterm and term infants with respiratory distress at birth

Yasa,

Kersin,

Cetinkaya

et al. 2024

Pediatric Pulmonology

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BackgroundMeasurement of regional pulmonary oxygen saturation by near‐infrared spectroscopy is a novel monitorization method. This study aimed to determine the early regional pulmonary oxygen saturations in neonates with respiratory distress.MethodsThis observational study was conducted at the delivery room in infants above 35 weeks of gestation who developed respiratory distress immediately after birth. Preductal oxygen saturation (Covidien Nellcor®) and regional oxygen saturations of both apical (raSO2) and basal regions (rbSO2) of right lung were measured (Covidien INVOS®) within the first 15 min of life and compared to those of healthy neonates.ResultsOf the 165 infants included to the study, 15 were late preterm and 55 developed respiratory distress. Infants with respiratory distress had significantly lower gestational age and birth weight. Regional pulmonary oxygenations at both apex and basal lung areas were positively correlated with SpO2 in all infants. The rbSO2 was significantly lower than raSO2 until 10th minute of life regardless of respiratory distress. The fractionized tissue oxygen extraction of both apical and basal lung areas was significantly higher in infants with respiratory distress until 5th minute of life.ConclusionThis study is one of the pioneer studies evaluating the early pulmonary oxygenation values of infants with respiratory distress. Oxygenation of apical lung regions are better than basal areas. Higher fractionized tissue oxygen extraction showed the impaired pulmonary perfusion in infants with respiratory distress.

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Noninvasive Monitoring Strategies for Bronchopulmonary Dysplasia or Post-Prematurity Respiratory Disease: Current Challenges and Future Prospects

Zini,

Miselli,

Berardi

2023

Children

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Definitions of bronchopulmonary dysplasia (BPD) or post-prematurity respiratory disease (PPRD) aim to stratify the risk of mortality and morbidity, with an emphasis on long-term respiratory outcomes. There is no univocal classification of BPD due to its complex multifactorial nature and the substantial heterogeneity of clinical presentation. Currently, there is no definitive treatment available for extremely premature very-low-birth-weight infants with BPD, and challenges in finding targeted preventive therapies persist. However, innovative stem cell-based postnatal therapies targeting BPD-free survival are emerging, which are likely to be offered in the first few days of life to high-risk premature infants. Hence, we need easy-to-use noninvasive tools for a standardized, precise, and reliable BPD assessment at a very early stage, to support clinical decision-making and to predict the response to treatment. In this non-systematic review, we present an overview of strategies for monitoring preterm infants with early and evolving BPD-PPRD, and we make some remarks on future prospects, with a focus on near-infrared spectroscopy (NIRS).

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Regional pulmonary oxygen saturations immediately after birth

Cited by 4 publications

References 26 publications

The diagnostic value of pulmonary near‐infrared spectroscopy in the early distinction of neonatal pneumonia from transient tachypnea of the newborn

The diagnostic value of pulmonary near‐infrared spectroscopy in the early distinction of neonatal pneumonia from transient tachypnea of the newborn

Regional pulmonary oxygen saturations in late preterm and term infants with respiratory distress at birth

Noninvasive Monitoring Strategies for Bronchopulmonary Dysplasia or Post-Prematurity Respiratory Disease: Current Challenges and Future Prospects

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