Regional Ventilation-Perfusion Relationships

Secker-Walker, Roger H.; Alderson, Philip O.; Jp, Wilhelm; Hill, Rexford L.; Markham, Joanne

doi:10.1159/000193661

Cited by 9 publications

(3 citation statements)

References 3 publications

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“…This supposition includes the fact that we must consider this point as a control one, or nor mal, which is not certainly the case in a pa tient. Meanwhile, our results are the same as those published by others for controls [20,23,26] and for emphysema [2,4,5,12,21]: decreasing from the apex to the base.…”

Section: Discussionsupporting

confidence: 92%

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Evaluation of the Distribution of Air and Blood in Emphysema Patients Using Radioisotopic Tracers

Laval¹,

Poirier²,

Feliciano³

et al. 1978

Respiration

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Continuous recording of the respiratory cycle with the simultaneous or sequential radionucleic exploration (gamma camera) of ventilation (¹³³Xe) and perfusion (MAT-99) was performed to determine the V/Q index in regional areas (Polaroid photography, mini-computer, memory visualization system, Benson incremental tracer, etc.) from the level of 1,024 points. An average ratio per sector was calculated and onyl three median sectors were retained. The wash-in and wash-out curves were traced by computer, and the calculation of the average T 1/2 for the different compartments of each median sector (apex – middle and base) was done in about 22 observations: in 18 diffuse emphysema, 11 of which were associated with giant cystic emphysema (spirometric, plethysmographic and radiographic data), T 1/2 values were greater than those of normal subjects (compartments C1 and C2) in diffuse emphysema and can become indefinable in zones of cystic emphysema. The values of the index V/Q approach the normal in diffuse emphysema with a tendency toward equalization of the ratios from the apex to the base. Extremely large divergence is observed in the elevated V/Q ratios in cystic emphysema. The values of the index V/Q approach the normal in diffuse emphysema with a tendency toward equalization of the ratios from the apex to the base. Extremely large divergence is observed in the elevated V/Q ratios in cystic emphysema.

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Section: Discussionsupporting

confidence: 92%

“…As it was done by others [20][21][22][23][24][25][26], we tried to find a segmentary ventilation/ perfusion index. This index (V /0) is de fined as the ratio of segmentary percentage of xenon activity to MAT-99 activity.…”

Section: Segmentary Ventilation/perfusion Indexmentioning

confidence: 99%