Regioselective Synthesis of a New Class of N -Arylsulfonylaminated Biheterocycles

Elgemeie, Galal H.; Sayed, Shahinaz Hassan

doi:10.1080/10426500307914

Cited by 6 publications

(3 citation statements)

References 4 publications

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“…Reaction of cyanoaceto- N -arylsulfonylhydrazide 384 with 2-((thiophen-2-yl)methylene) malononitrile furnished 90% of N -phenylsulfonylamino-2-pyridone 385 (Scheme ) …”

Section: Reactions Of Acid Hydrazidesmentioning

confidence: 99%

Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings

et al. 2014

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“…Reaction of cyanoaceto- N -arylsulfonylhydrazide 384 with 2-((thiophen-2-yl)methylene) malononitrile furnished 90% of N -phenylsulfonylamino-2-pyridone 385 (Scheme ) …”

Section: Reactions Of Acid Hydrazidesmentioning

confidence: 99%

Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings

et al. 2014

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“…The synthetic routes aimed to achieve the target organic compounds (II) and (III) are displayed in Schemes 1. The 1,6-diamino-2-oxo-4-(thiophen-2-yl)-1,2-dihydropyridine-3,5-dicarbonitrile A is employed as the starting material, that formed according to literature method [20] via cyclocondensation by reaction of 2-(thiophen-2-ylmethylene) malononitrile with cyanoaceto-hydrazide in ethyl alcohol solution catalyzed by addition of few drops of pipridine (Scheme 1).…”

Section: Resultsmentioning

confidence: 99%

“…The starting material [I] was prepared as stated in the literature method [20]. A mixture of cyanoacetohydrazide (5 mmol) and 2-(thiophen-2-ylmethylene) malononitrile (5 mmol) in ethanolic solution (15 mL) catalyzed by a few drops of pipridine is re uxed for 3hrs.…”

Section: Synthesis Of the Target Organic Compoundsmentioning

confidence: 99%

Synthesis, characterization and evaluation the performance of some novel pyridinone derivatives as corrosion inhibitors in some petroleum applications

Darwish

Ammar

Al-Sharbasy

et al. 2022

Preprint

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In this paper, newly synthesized pyridinone derivatives namely; 6-amino-2-oxo-1-(((1-phenyl-3-(p-tolyl)-1H-pyrazol-4-yl) methylene) amino)-4-(thiophen-2-yl)-1,2-dihydropyridine-3,5-dicarbo- nitrile (II) and 6-amino-1-(((2-chloro-7-ethoxyquinnolin-3-yl) methylene) amino)-2-oxo-4-(thiophen-2-yl)-1,2-dihydropyridine-3,5-dicarbonitrile (III) were synthesized in laboratory and their chemical structure were characterized via elemental analysis, FTIR, 1H- and 13C -NMR spectroscopic analysis tools. The performance of the newly synthesized pyridinone derivatives as anticorrosion for carbon steel alloys in 2 M HCl aggressive medium were carried out using weight loss measurement as chemical testing method, in addition to PDP and EIS as electrochemical measurements. The collected data revealed that these pyridinone derivatives operated as excellent anticorrosion for metallic structures. PDP results revealed that these pyridinone derivatives behave as mixed type inhibitors. The adsorption isotherm revealed that undertaken compounds obeyed Langmuir adsorption isotherm. EIS data confirmed that the values charge transfer resistance (Rct) was increased by increasing the concentration of the injected inhibitor molecules, while the electrochemical double layer (Cdl) was dramatically decreased. The work was supported by two surface analysis methods such as SEM and EDX. Finally, a suitable inhibition mechanism was assumed and discussed in details.

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Sulfa drug analogs: new classes of N-sulfonyl aminated azines and their biological and preclinical importance in medicinal chemistry (2000–2018)

2019

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Regioselective Synthesis of a New Class of N -Arylsulfonylaminated Biheterocycles

Cited by 6 publications

References 4 publications

Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings

Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings

Synthesis, characterization and evaluation the performance of some novel pyridinone derivatives as corrosion inhibitors in some petroleum applications

Sulfa drug analogs: new classes of N-sulfonyl aminated azines and their biological and preclinical importance in medicinal chemistry (2000–2018)

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