Regioselective synthesis of indazolo[2,3-a]quinazolines enabled by I₂/S-facilitated annulation relay dehydrogenative aromatization of cyclohexanones

Abstract

A concise and efficient entrance to the indazolo[2,3-a]quinazolines has been developed via a sequential annulation of 3-aminoindazoles and dehydrogenative aromatization of cyclohexanones. This high regioselectivity is attributed to the fact...