Regression Modeling of Competing Risks Survival Data in the  Presence of Covariates Based on a Generalized Weibull Distribution:  A Simulation Study

Moamer, Soraya; Baghestani, Ahmad Reza; Pourhoseingholi, Mohamad Amin

doi:10.18187/pjsor.v14i2.1929

Cited by 4 publications

(2 citation statements)

References 17 publications

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“…However, postdiagnosis BMI was not associated with CRC mortality [29]. In a retrospective study in Iran, the results indicated that the BMI had a statistically significant GMJ.2019;8:e1413 www.gmj.ir effect on survival time, and decreasing BMI would increase the risk of patient's death from CRC [30]. In this study, the BMI has a meager significant impact on cure rate of patients with CRC; thus, an increase in BMI leads to a slight increase in cure probability of patients.…”

Section: Discussionmentioning

confidence: 99%

Mismeasured Covariate in the Long-Term Survival of Colorectal Cancer

Azizmohammad Looha,

Pourhoseingholi,

Hosseini

et al. 2019

GMJ

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Background: Colorectal cancer (CRC) is one of the most important causes of morbidity and mortality worldwide. This study aimed to determine the effect of measurement error of risk factors on the cure fraction of CRC patients. Materials and Methods: This study was conducted using the medical records of 346 patients with CRC, who were followed up between 2006 and 2017 in Shiraz, Iran. In our data, lymph node ratio (LNR) was a characteristic measuring with error. This variable was used in the model with 0.04 and 0.8 of error variance. Nonmixture nonparametric cure rate model and its corrected forms, simulation-extrapolation (SIMEX) and corrected score (CS), were applied to the data. Results: In noncured cases, the mean survival time was 1115.45 (95% confidence interval, 1043.60-1187.30) days. The 1-, 3-, and 5-year survival rates were 0.93, 0.71, and 0.65, respectively. The proportion of cured patients was 65.2%. The SIMEX method did not change the effect of LNR substantially on cure fraction as compared with the naive method when the variance of measurement error was 0.04 and 0.80. The CS method changed the effect of LNR on cure fraction even when the variance of measurement error was 0.04. Conclusion: The best method to assess the effect of LNR on cure fraction was the naive method, and the CS method was not deemed to be a valid method to correct the measurement error in LNR. [GMJ.2019;8:e1413]Â Â Â

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Section: Discussionmentioning

confidence: 99%

Mismeasured Covariate in the Long-Term Survival of Colorectal Cancer

Azizmohammad Looha,

Pourhoseingholi,

Hosseini

et al. 2019

GMJ

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“…However, few studies revealed that the risk of death is undistinguishable for men and women as well [18][19][20][21]…”

Section: Based On An Examination Of Numerous Factorsmentioning

confidence: 99%

Colorectal cancer survival in Thailand

Monkhan,

Phimha,

Prasit

et al. 2024

IJPHAP

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Background: Colorectal cancers are third among the world's most common cancers. Among the top five most common malignancies in Thailand, colorectal cancer primarily affects the elderly but affects persons of all ages as well. In addition, its incidence is rising yearly. Objectives: This retrospective cohort study aimed to describe the survival rate of Colorectal cancer patients in Thailand. Methods: The study used secondary data from the Ministry of Public Health between 2013 and 2020, a total of 57,321 cases were enrolled. Descriptive statistical analysis and inferential statistical analysis were performed by Cox regression analysis to observe survival rate estimate, Kaplan-Meier Survival estimate with 95% CI. Results: Among the total participants, 51.28% were male. Female survival rate was 9% higher than male Colorectal cancer patients (HR = 0.91, 95% CI: 0.86-0.94). The Colorectal cancer patients who were aged 61-70 years were more likely to pass away than patients aged £ 60 years (HR= 1.25, 95% CI:1.17- 1.34). Similarly, Colorectal cancer patients aged ≥70 years were more likely to have demise 1.58 times earlier than patients aged £ 60 years (HR= 1.58, 95% CI: 1.49-1.68). Conclusion: The survival rate of patients with colorectal cancer was significantly affected by gender. In addition, age was one of the variables which is also statistically significant that impacted on the colorectal cancer patient survival rate. Therefore, the formulation of screening policies for colorectal cancer in targeted populations, particularly in elderly should be established to support colorectal cancer prevention and reduce the risk to achieve a greater health impact among them.

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