Regression of Inflammatory Myofibroblastic Tumor of the Gastrointestinal Tract Under Infliximab Treatment

Germanidis, Georgios; Xanthakis, Ioannis; Tsitouridis, Ioannis; Zaramboukas, Thomas; Kiskinis, Dimitrios; Konstantaras, Christos; Miliaras, S.; Sirakos, Theodoros; Pagkalos, Emmanouil

doi:10.1007/s10620-005-1593-1

Cited by 44 publications

(27 citation statements)

References 17 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The prognosis is poor if there is local recurrence as IMFT does not respond to chemotherapy and radiotherapy. Promising results with anti-inflammatory agents [6] and anti-tumour necrosis factor-α binding antibodies [7] have been published recently.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory myofibroblastic tumour: an imaging dilemma (2010: 5b)

Rasalkar

Chu

et al. 2010

Eur Radiol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Inflammatory myofibroblastic tumour: an imaging dilemma (2010: 5b)

Rasalkar

Chu

et al. 2010

Eur Radiol

View full text Add to dashboard Cite

show abstract

“…For non-excisable lesions, several medical treatments, including chemotherapy, radiation therapy, nonsteroidal anti-inflammatory drugs, corticosteroids and antitumor necrosis factor-binding antibodies, have been previously administered to palliate or shrink these IMTs to a resectable size and configuration (6,7,9). However, the medical treatment is not clearly defined due to a lack of strong statistical evidence, and palliative treatment programs cannot be recommended as a standard regimen (22,23). Based on the recent advances in ALK inhibitors and other ALK target genes, these therapies may be more effective, and thus may be offered to patients with IMT instead (16).…”

Section: B a Discussionmentioning

confidence: 99%

Inflammatory myofibroblastic tumor in the head of the pancreas with anorexia and vomiting in a 69-year-old man: A case report

Ding

Tian

2016

Oncology Letters

View full text Add to dashboard Cite

Abstract. Inflammatory myofibroblastic tumor (IMT) is a rare condition of unclear etiology that is commonly observed in the lung but rarely in the pancreas. WHO classified IMT as a potentially malignant or aggressive tumor. In the present report, the case of a 69-year-old male patient with an IMT in the head of the pancreas, who experienced anorexia, nausea and vomiting, is presented. The patient's clinical symptoms were nonspecific, and the imaging findings revealed a hypovascularized pancreatic mass with stenosis of the descending duodenum. The electronic endoscopy findings revealed protruding lesions in the duodenal bulb and the descending duodenum. Biopsies of the mass were conducted with an electronic endoscope, but were not diagnostic. Subsequent duodenopancreatectomy aided in determining a pathological diagnosis of IMT, based on the histology and immunohistochemistry results. The patient experienced a recovery without further incident, as observed during a regular follow-up 3 years later. IMT in the head of the pancreas is rare, particularly in adults. In the present study, an extremely rare case of IMT involving the head of the pancreas in an adult patient is presented, and the therapeutic options for this condition are discussed.

show abstract

“…Various different chemotherapy regimens have been used including etoposide, vincristine, cisplatin, adriamycin and methotrexate with varying degrees of success [25]. There are also reports of disease control with thalidomide [26] and infliximab [16]. Corticosteroids [27] and non-steroidal anti-inflammatory drugs [28] have been reported to induce disease regression.…”

Section: Discussionmentioning

confidence: 99%

A Rare Cause of an Endobronchial Tumour in Children: The Role of Interventional Bronchoscopy in the Diagnosis and Treatment of Tumours while Preserving Anatomy and Lung Function

Breen

Dubus²,

Chetaille³

et al. 2007

Respiration

View full text Add to dashboard Cite

An 11-year-old girl was referred to our institution with complete obstruction of the left main stem bronchus by an endoluminal mass and was successfully treated by a combination of laser and mechanical debulking. Coring of the mass both allowed histological diagnosis (inflammatory myofibroblastic tumour) and definitive treatment with no recurrence after 3 years of follow-up. This case report emphasizes the major role of interventional bronchoscopy in the management of tumoural obstruction in children in whom benign conditions are frequent. Interventional bronchoscopy, which is minimally invasive when compared to surgery, in the vast majority of cases allows a precise diagnosis as it provides large samples of tissue removed during coring; in some cases it can be curative by itself and preserves lung parenchyma and function.

show abstract

Regression of Inflammatory Myofibroblastic Tumor of the Gastrointestinal Tract Under Infliximab Treatment

Cited by 44 publications

References 17 publications

Inflammatory myofibroblastic tumour: an imaging dilemma (2010: 5b)

Inflammatory myofibroblastic tumour: an imaging dilemma (2010: 5b)

Inflammatory myofibroblastic tumor in the head of the pancreas with anorexia and vomiting in a 69-year-old man: A case report

A Rare Cause of an Endobronchial Tumour in Children: The Role of Interventional Bronchoscopy in the Diagnosis and Treatment of Tumours while Preserving Anatomy and Lung Function

Contact Info

Product

Resources

About