Regression of Serous Macular Detachment Due to Peripheral Exudative Hemorrhagic Chorioretinopathy following Intravitreal Bevacizumab

Barkmeier, Andrew J.; Kadikoy, Hüseyin; Holz, Eric R.; Carvounis, Petros

doi:10.5301/ejo.2011.6246

Cited by 10 publications

(1 citation statement)

References 7 publications

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“…Anti-vascular endothelial growth factor treatment has yielded variable outcomes in terms of restoring visual acuity. [19][20][21] In the present study, antivascular endothelial growth factor treatment was not statistically associated with visual prognosis.…”

Section: Discussioncontrasting

confidence: 69%

Peripheral Exudative Hemorrhagic Chorioretinopathy in Asian Populations

Choi¹,

Lee²,

Byeon³

et al. 2023

Retina

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Purpose: Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is a rare degenerative disease that affects the peripheral retina. Reports of PEHCR in Asian patients are rare. Thus, the aim of this study was to investigate the clinical characteristics and outcomes of PEHCR in Asian patients.Methods: A retrospective chart review of 33 eyes of 29 Asian patients with PEHCR.Results: The mean age of the patients was 70 years, and 75.9% of them were women. Vitreous hemorrhage occurred in 51.5% of eyes during a mean follow-up of 43.1 months. The occurrence of vitreous hemorrhage was associated with a thicker baseline subfoveal choroid (P = 0.001) and the male sex (P = 0.005). Final visual acuity was less than 20/200 in 29.2% of eyes. The predictive factors for a final visual acuity worse than 20/200 included poor initial visual acuity (P = 0.002), initial lesion involvement of more than 180°of the peripheral retina (P = 0.03), an extension of subretinal hemorrhage to the macula (P = 0.040), and absence of complete tumor regression (P = 0.02).Conclusion: Asian PEHCR patients seem to be more frequently associated with vitreous hemorrhages, especially in male patients with thicker choroids. Although PEHCR was largely self-limiting, approximately one-third of the eyes ended up with a visual acuity of less than 20/200 with extensive lesion involvement.

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Section: Discussioncontrasting

confidence: 69%