Regret and Quality of Life After Mastectomy With or Without Reconstruction

Fortunato, Lucio; Loreti, Andrea; Cortese, Giuliana; Spallone, Diana; Toto, Vito; Cavaliere, F.; Farina, Massimo; Pinta, Massimo La; Manna, Elena; Detto, Laura; Pallara, Tiziano

doi:10.1016/j.clbc.2019.11.005

Cited by 40 publications

(18 citation statements)

References 26 publications

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“…Treating breast cancer with a mastectomy resulting in the loss of a breast disrupts the harmony of the feminine body structure which has the potential to cause dramatic effects on a woman's selfidentity affecting body image, psychosocial well-being, and sexual well-being (57)(58)(59)(60). In 1998, The Women's Health and Cancer Rights Act (WHCRA), a federal law mandating all payer coverage with the opportunity to undergo breast reconstruction following mastectomy, was passed (60).…”

Section: Breast Reconstructionmentioning

confidence: 99%

Current Surgical Innovations in the Treatment of Breast Cancer

Crystal¹,

Mella-Catinchi²,

Xu³

et al. 2022

Breast Cancer

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Surgery is an essential component in the management of treatable breast cancer. With the use of standardized staging and data collection, evidence-based management of breast cancer has evolved to limit treatments to what is necessary but sufficient to allow tissue preservation and control of treatment-specific morbidity. As more tumors are discovered by pretreatment imaging and are not identifiable on physical exam, intraoperative tumor localization techniques have become increasingly sophisticated and reliable. Techniques for localization of "sentinel" nodes has become increasingly accurate and technically less complicated. Surgical treatment may occur Note to the reader: This chapter is part of the book Breast Cancer (ISBN: 978-0-6453320-3-2), scheduled for publication in July 2022. The book is being published by Exon Publications,

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Section: Breast Reconstructionmentioning

confidence: 99%

Current Surgical Innovations in the Treatment of Breast Cancer

Crystal¹,

Mella-Catinchi²,

Xu³

et al. 2022

Breast Cancer

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“…Mastectomy represents a deep burden for women with breast cancer. Very little is known about the psychological consequences over time and the QOL of women so treated, with or without breast reconstruction (BR) [ 8 ]. Conflicting literature is available regarding QOL after mastectomy.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Quality of Life in Patients of Mastectomy With Chemotherapy

Deshpande¹,

Shinde²,

Deo³

et al. 2022

Cureus

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Background: Breast cancer is one of the most common cancers in India as well as the world. In India, 48% of patients with breast cancer are below 50 years of age, indicating a huge age shift in the last 25 years. Breast cancer in an early age group increased the five-year survival rate and increased life expectancy has created a large group of breast cancer survivors who battle scars of disease as well as treatment. Standardized multimodal treatment is either not affordable or not available, so the breast conservation surgery rate is very low. Mastectomy is still the most common modality of treatment, particularly in rural areas. In addition to psychological, social, economic, and family barriers to obtaining the diagnosis and treatment needed, economic barriers like the cost of travel and lost wages are important factors influencing the choice of treatment. Mastectomy represents a deep burden for women with breast cancer. Very little is known about the psychological consequences over time and the quality of life (QOL) of women so treated, with or without breast reconstruction. Conflicting literature is available regarding QOL after mastectomy. The survival rates of breast cancer are increasing. They are reported in the range of 80-90% in western countries while in the range of 60% in the Indian scenario. With high survival rates in cancer, the focus needs to shift from mortality indicators to QOL indicators. The QOL that these survivors experience is a comparatively newer domain of study. Though there are many instruments for assessment of breast QOL of breast cancer patients with numerous studies in western literature, QOL studies in Indian rural population are far less, and urban studies cannot be extrapolated because the method of treatment differs, with breast conservation being more common in urban population. Hence, the present study is undertaken to assess the QOL in patients who have undergone mastectomy and ongoing chemotherapy or completed chemotherapy recently using a relatively newer instrument, i.e., the Quality of Life Instrument -Breast Cancer Patient version.Methodology: The present study was a cross-sectional study conducted at a rural tertiary healthcare center on mastectomy patients attending the outpatient department and admitted to the hospital. All the female patients of carcinoma breast treated with a mastectomy who were receiving the adjuvant or neoadjuvant chemotherapy or were within one year of completion of chemotherapy irrespective of age at diagnosis were included in this study. The assessment was performed by interview method using a questionnaire.Results: In this study, 44.90% of the patients were <50 years old and 55.10% were more than 50 years old. Among them, 28.57% were illiterate while only 20.41% had graduate education. The majority (61.22%) were from the low socioeconomic class. Majority of women presented in the late stages of the disease, with 61.22% presenting in the third stage and only three (6.12%) presenting in the first stage of the disease. The overall global QOL sc...

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“…Despite significant advances in screening, diagnostic, and cancer therapies the total mastectomy numbers remain high [4]. Breast reconstruction after mastectomy has a significant positive impact on the long-term body image, quality of life, and psychological health of affected women [5,6]. Despite clear evidence of superior long-Disclaimer/Publisher's Note: The statements, opinions, and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s).…”

Section: Introductionmentioning

confidence: 99%

Is it all about Surface Topography? An Intraindividual Clinical Outcome Analysis of Two Different Implant Surfaces in Breast Reconstruction

Schoberleitner¹,

Augustin²,

Egle³

et al. 2022

Preprint

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The most common long-term complication of silicone breast implants (SMI) remains capsular fibrosis. The etiology of this exaggerated implant encapsulation is multifactorial but primarily induced by the host response towards the foreign material silicone. Identified risk factors included specific implant topographies. Of note, breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), has only been observed in response to textured surface implants. We hypothesize that reduction of SMI surface roughness causes less host response hence better cosmetic outcome with fewer complications for the patient. A total of 7 patients received the routinely used CPX®4 breast expander (~60 µM Ra) and the novel SmoothSilk® (~ 4 µM Ra), fixed prepectoral with a titanised mesh pocket and randomized to the left or right breast after bilateral prophylactic NSME (nipple-sparing mastectomy). We aimed to compare the postoperative outcome regarding capsule thickness, seroma formation, rippling, implant dislocation as well as comfortability and practicability. Our analysis shows that surface roughness is an influential parameter in controlling fibrotic implant encapsulation. First time intra-individually compared in patients, our data confirm an improved biocompatibility with minor capsule formation around SmoothSilk® implants with an average shell roughness of 4 µM and in addition an amplification of host response by titanised implant pockets.

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Regret and Quality of Life After Mastectomy With or Without Reconstruction

Cited by 40 publications

References 26 publications

Current Surgical Innovations in the Treatment of Breast Cancer

Current Surgical Innovations in the Treatment of Breast Cancer

Assessment of Quality of Life in Patients of Mastectomy With Chemotherapy

Is it all about Surface Topography? An Intraindividual Clinical Outcome Analysis of Two Different Implant Surfaces in Breast Reconstruction

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