We consider the problem of determining the possible orders for k-regular, k-connected and bipancyclic subgraphs of the hypercube Qn. For k = 2 and k = 3, the solution to the problem is known. In this paper, we solve the problem for k = 4 by proving that Qn has a 4-regular, 4-connected and bipancyclic subgraph on l vertices if and only if l = 16 or l is an even integer such that 24 ≤ l ≤ 2 n . Further, by improving a result of Ramras, we prove that a k-regular subgraph of Qn is either isomorphic to Q k or has at least 2 k + 2 k−1 vertices. We also improve a result of Mane and Waphare regarding the existence of a k-regular, k-connected and bipancyclic subgraph of Qn. Some applications of our results are given.