Regular Exercise as an Effective Approach in Antihypertensive Therapy

Ketelhut, Reinhard G.; Franz, I.-W.; Scholze, Jürgen

doi:10.1249/01.mss.0000106173.81966.90

Cited by 55 publications

(34 citation statements)

References 23 publications

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“…It is well documented that multiple bouts of moderate-tovigorous intensity exercise can result in chronic favourable adaptations in those with elevated BP [13,14]. As early as 1898, Leonard Hill of the London Hospital Medical College published the results of a man who ran 400 yards as fast as possible and recorded a 10−15 mmHg reduction in resting BP 10 min after the run [15].…”

Section: Discussionmentioning

confidence: 99%

Influence of a high-intensity interval training session on peripheral and central blood pressure at rest and during stress testing in healthy individuals

Ketelhut

Milatz

Heise

et al. 2016

Vasa

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Summary:Background: Regular physical activity is known to reduce arterial pressure (BP). In a previous investigation, we could prove that even a single bout of moderate-intensity continuous exercise (MICE) causes a prolonged reduction in BP. Whether high-intensity interval training (HIIT) has a favourable infl uence on BP, and therefore may be followed subjects and methods by a prolonged BP reduction, should be examined on the basis of blood pressure response after exercise and during a subsequent stress test. Patients and methods: In 39 healthy men (aged 34 ± 8 years, BMI 24 ± 2), peripheral and central BP were measured noninvasively at rest and at the end of a 2-min cold pressor test (CPT) using a Mobil-O-Graph (24 PWA monitor, IEM). Following HIIT (6 x 1 min at 98% of the previously determined maximum wattage, 4-min rest between intervals) BP was measured again throughout 60 min of rest and thereafter during a CPT. The results were compared with those obtained before HIIT. Results: Similar to MICE, peripheral and central BPs were signifi cantly (p < 0.05) lower 45 min after HIIT. When analysing peripheral BP during a CPT before and after exercise, signifi cantly lower systolic (p < 0.001) and diastolic (p = 0.008) pressures were established after HIIT. This was true for systolic (p = 0.002) and diastolic (p = 0.006) central BP as well. Although there were no more signifi cant differences between pressures at rest before and 60 min after exercise, the increase in peripheral systolic pressure due to CPT was signifi cantly slower after HIIT (p = 0.019) when compared with BP during CPT before exercise. This was true for central systolic BP as well (p = 0.017). Conclusion: HIIT leads to a BP reduction, which can still be detected up to 45 min after completion of the training. Even 60 min after exercise, pressures during a CPT showed a reduced augmentation, indicating an attenuated hemodynamic response to stress testing after HIIT.

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Section: Discussionmentioning

confidence: 99%

Influence of a high-intensity interval training session on peripheral and central blood pressure at rest and during stress testing in healthy individuals

Ketelhut

Milatz

Heise

et al. 2016

Vasa

Self Cite

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“…In fact, current public health guidelines for the prevention of dyslipidaemia recommend physical exercise of moderate intensity [17]. In addition, effects of aerobic exercise on serum lipid levels in individuals with hypertension have been well-reported in the literature [18][19][20][21]. However, only a few studies on the effects of aerobic exercise on serum lipid levels reported the use of antihypertensive drugs by the participants [14,22].…”

Section: Introductionmentioning

confidence: 99%

A Randomized Controlled Trial of the Effects of Aerobic Dance Training on Blood Lipids Among Individuals with Hypertension on a Thiazide

Maruf

Akinpelu

Salako

2014

High Blood Press Cardiovasc Prev

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“…Physical activity is commonly regarded as beneficial to both physical and psychological health, and is seen as an effective preventive measure and treatment for stress-related diseases (Perkins et al, 1986;Ross and Hayes, 1988;Steptoe et al, 1993;Blumenthal et al, 1999;Babyak et al, 2000;Talbot et al, 2002;Ketelhut et al, 2004;Barlow et al, 2006;Nabkasorn et al, 2006). Physically active people show reduced reactivity to physical stressors as well as reduced susceptibility to the adverse influences of life stress (Tucker et al, 1986;Luger et al, 1987;Deuster et al, 1989;Steptoe et al, 1989;Dishman, 1997;Throne et al, 2000;Dishman et al, 2006;Rimmele et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

The level of physical activity affects adrenal and cardiovascular reactivity to psychosocial stress

Rimmele

Seiler

Marti

et al. 2009

Psychoneuroendocrinology

232

155

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Regular Exercise as an Effective Approach in Antihypertensive Therapy

Abstract: The data demonstrate that long-term aerobic exercise is associated with a decrease in BP at rest and during exercise, which is comparable to that of drug therapies. This antihypertensive effect of regular training can be maintained as long as 3 yr.

Cited by 55 publications

References 23 publications

Influence of a high-intensity interval training session on peripheral and central blood pressure at rest and during stress testing in healthy individuals

Influence of a high-intensity interval training session on peripheral and central blood pressure at rest and during stress testing in healthy individuals

A Randomized Controlled Trial of the Effects of Aerobic Dance Training on Blood Lipids Among Individuals with Hypertension on a Thiazide

The level of physical activity affects adrenal and cardiovascular reactivity to psychosocial stress

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