Regular Physical Activity and Risk of Atrial Fibrillation

Abstract

Background-Although previous studies have suggested that competitive athletes have a higher risk of atrial fibrillation than the general population, limited and inconsistent data are available on the association between regular physical activity and the risk of atrial fibrillation. Methods and Results-A systematic, comprehensive literature search was performed using MEDLINE, EMBASE, and COCHRANE until 2011. Extracted data from the eligible studies were meta-analyzed using fixed effects model. Four studies, which included 95 526 subjects, were eligible for meta-analysis. For all of the studies included, the extreme groups (ie, maximum versus minimal amount of physical activity) were used for the current analyses. The total number of participants belonging to the extreme groups was 43 672. The pooled odds ratio (95% confidence interval) for atrial fibrillation among regular exercisers was 1.08 (0.97-1.21). Conclusions-Our data do not support a statistically significant association between regular physical activity and increased incidence of atrial fibrillation. (Circ Arrhythm Electrophysiol. 2013;6:252-256.)

Cardiorespiratory Fitness and Risk of Incident Atrial Fibrillation

“…by guest on May 12, 2018 http://circ.ahajournals.org/ Downloaded from risk of AF among obese individuals with lower levels of CRF. With increasing levels of CRF, however, this risk gradually declined so that their risk of AF closely approached that of nonobese individuals.…”

“…34 The mechanisms explaining the association between exercise and AF have not been fully elucidated, but inflammation, atrial remodeling, and autonomic imbalance are among those most commonly cited.…”

“…Model 1 was adjusted for age, sex, and race (white, black, other). Model 2 was adjusted for model 1 covariates and history of hypertension, diabetes mellitus, sedentary habits, obesity, family history of CAD, smoking, by guest on May 12, 2018 http://circ.ahajournals.org/ Downloaded from hyperlipidemia, known CAD, hypertensive response, and chronotropic incompetence. Model 3 was adjusted for the covariates of model 2 and thyroid medications, digoxin, treated lung disease, β-blocker use, angiotensin-converting enzyme inhibitor use, angiotensin receptor blocker use, calcium channel blocker use, and use of all lipid-lowering medications, including statins.…”

“…32,33 Potential "cardiotoxicity" resulting from excessive participation in endurance exercise has been described by O'Keefe et al 14 Most epidemiological studies, however, have failed to show a higher risk for AF with exercise training in general populations, likely owing to an underrepresentation of highly trained athletes and resultant selection bias. 34 The mechanisms explaining the association between exercise and AF have not been fully elucidated, but inflammation, atrial remodeling, and autonomic imbalance are among those most commonly cited.…”

Przypadkowo wykryte napadowe migotanie przedsionków

“…Czynniki ryzyka izolowanego AF występującego poniżej 60. roku życia są słabiej udokumentowane. Rozważano wpływ używek (alkoholu, marihuany, palenia tytoniu), masy ciała, cech osobowości, aktywności fizycznej [2][3][4][5]. Żadnego z powyższych czynników ryzyka nie stwierdzono u opisywanego pacjenta.…”