Régulation des récepteurs et mécanismes d'action de l'hormone de croissance

Presence of specific growth hormone binding sites in rainbow trout (Oncorhynchus mykiss) tissues: Characterization of the hepatic receptor

“…Fryer and Bern (1979) and more recently Gray et al (1989) demonstrated that specific binding of GH is lower in stunted than in normal coho salmon. In mammals, variations of GH binding were also observed during pregnancy (Posner, 1976;Gerasimo et al, 1979) and starvation (see Postel-Vinay et al, 1987). All the properties observed with the trout liver preparation, a finite number of binding sites, high affinity, and hormone specificity, are characteristic of hormonal receptors.…”