Regulation of CRISPR edited food and feed: legislation and future

Ghouri, Muhammad Zubair; Munawar, Nayla; Aftab, Syed Ovais; Ahmad, Aftab

doi:10.1016/b978-0-12-823903-2.00004-4

Cited by 4 publications

(2 citation statements)

References 81 publications

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“…In recent times, the biotechnology revolution and industrial transformation grew rapidly. Genome editing technology is actively used to improve crops; however, the release of such crops on the market or in the environment is of concern [ 40 ]. Thus, there was a need to detect genome-edited (GenEd) crops.…”

Section: Applications Of the Versatile Crispr-cas Rna Targeting Systemsmentioning

confidence: 99%

RNA-Dependent RNA Targeting by CRISPR-Cas Systems: Characterizations and Applications

Gunitseva

Evteeva

Borisova

et al. 2023

IJMS

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Genome editing technologies that are currently available and described have a fundamental impact on the development of molecular biology and medicine, industrial and agricultural biotechnology and other fields. However, genome editing based on detection and manipulation of the targeted RNA is a promising alternative to control the gene expression at the spatiotemporal transcriptomic level without complete elimination. The innovative CRISPR-Cas RNA-targeting systems changed the conception of biosensing systems and also allowed the RNA effectors to be used in various applications; for example, genomic editing, effective virus diagnostic tools, biomarkers, transcription regulations. In this review, we discussed the current state-of-the-art of specific CRISPR-Cas systems known to bind and cleave RNA substrates and summarized potential applications of the versatile RNA-targeting systems.

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Section: Applications Of the Versatile Crispr-cas Rna Targeting Systemsmentioning

confidence: 99%

RNA-Dependent RNA Targeting by CRISPR-Cas Systems: Characterizations and Applications

Gunitseva

Evteeva

Borisova

et al. 2023

IJMS

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“…SDNs have the potential to aid in crop improvement and enhance food security in many sugar beet producing countries (Table 4). SDNs are categorised into SDN1, SDN2, and SDN3 based on the outcomes of genomic alterations and double strand break repair (Ghouri et al, 2023). SDN1 does not require template and causes gene disruptions via InDels (small insertions or deletions of bases).…”

Section: Introductionmentioning

confidence: 99%

Advancements and prospects of CRISPR/Cas9 technologies for abiotic and biotic stresses in sugar beet

Misra,

Mall,

Pandey

et al. 2023

Front. Genet.

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Sugar beet is a crop with high sucrose content, known for sugar production and recently being considered as an emerging raw material for bioethanol production. This crop is also utilized as cattle feed, mainly when animal green fodder is scarce. Bioethanol and hydrogen gas production from this crop is an essential source of clean energy. Environmental stresses (abiotic/biotic) severely affect the productivity of this crop. Over the past few decades, the molecular mechanisms of biotic and abiotic stress responses in sugar beet have been investigated using next-generation sequencing, gene editing/silencing, and over-expression approaches. This information can be efficiently utilized through CRISPR/Cas 9 technology to mitigate the effects of abiotic and biotic stresses in sugar beet cultivation. This review highlights the potential use of CRISPR/Cas 9 technology for abiotic and biotic stress management in sugar beet. Beet genes known to be involved in response to alkaline, cold, and heavy metal stresses can be precisely modified via CRISPR/Cas 9 technology for enhancing sugar beet’s resilience to abiotic stresses with minimal off-target effects. Similarly, CRISPR/Cas 9 technology can help generate insect-resistant sugar beet varieties by targeting susceptibility-related genes, whereas incorporating Cry1Ab and Cry1C genes may provide defense against lepidopteron insects. Overall, CRISPR/Cas 9 technology may help enhance sugar beet’s adaptability to challenging environments, ensuring sustainable, high-yield production.

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CRISPR/Cas Systems for Enhancing Photosynthesis: Climate Resilience and Food Production

Barupal,

Kumar

2024

Gene Editing in Plants

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Regulation of CRISPR edited food and feed: legislation and future

Cited by 4 publications

References 81 publications

RNA-Dependent RNA Targeting by CRISPR-Cas Systems: Characterizations and Applications

RNA-Dependent RNA Targeting by CRISPR-Cas Systems: Characterizations and Applications

Advancements and prospects of CRISPR/Cas9 technologies for abiotic and biotic stresses in sugar beet

CRISPR/Cas Systems for Enhancing Photosynthesis: Climate Resilience and Food Production

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