Regulation of shoot epidermal cell differentiation by a pair of homeodomain proteins in<i>Arabidopsis</i>

Abe, Mitsutomo; Katsumata, Hiroshi; Komeda, Yoshibumi; Takahashi, Taku

doi:10.1242/dev.00292

Cited by 336 publications

(391 citation statements)

References 35 publications

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“…Our molecular phylogenetic analysis of 16 AtHD-ZIP IV family members using Bayesian algorithms shows that, similar to the neighbor-joining analysis by Nakamura et al (Nakamura et al, 2006), HDG2 is most closely related to AtML1 and PDF2, two wellstudied L1 layer (protoderm)-specific genes (Abe et al, 2003;Lu et al, 1996) (supplementary material Fig. S1).…”

Section: Hdg2 Is a Meristemoid-expressed Nuclear Proteinsupporting

confidence: 73%

“…Autoregulation of transcription factors is crucial for robust specification of cell fate. AtML1 auto-activates by directly binding to the L1 box in its own promoter to reinforce protodermal identity (Abe et al, 2003;Takada and Jürgens, 2007). That HDG2-OX triggers ectopic AtML1 expression (Fig.…”

Section: Research Articlementioning

confidence: 93%

“…It is surprising that an AtML1 overexpression phenotype has not been reported since its identification in 1996 (Lu et al, 1996). PDF2-OX confers a laterflowering phenotype, likely mimicking the effects of a distantly related AtHD-ZIP IV, FWA (Abe et al, 2003); thus, HDG2 may share more common targets with AtML1 than PDF2.…”

Section: Research Articlementioning

confidence: 99%

“…The epidermal layer is specified during embryogenesis. In Arabidopsis, two closely related genes, A. thaliana MERISTEM LAYER1 (AtML1) and PROTODERMAL FACTOR2 (PDF2), redundantly specify epidermal identity; their double loss of function results in an embryo that is lethally devoid of a protoderm (Abe et al, 2003). AtML1 and PDF2 belong to a family of plant-specific homeodomain leucine zipper class IV (HD-ZIP IV) transcription factors (Mukherjee et al, 2009), many showing preferential expression in the epidermis (Ingram et al, 2000;Javelle et al, 2011a;Nakamura et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

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Arabidopsishomeodomain-leucine zipper IV proteins promote stomatal development and ectopically induce stomata beyond the epidermis

et al. 2013

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SUMMARYThe shoot epidermis of land plants serves as a crucial interface between plants and the atmosphere: pavement cells protect plants from desiccation and other environmental stresses, while stomata facilitate gas exchange and transpiration. Advances have been made in our understanding of stomatal patterning and differentiation, and a set of 'master regulatory' transcription factors of stomatal development have been identified. However, they are limited to specifying stomatal differentiation within the epidermis. Here, we report the identification of an Arabidopsis homeodomain-leucine zipper IV (HD-ZIP IV) protein, HOMEODOMAIN GLABROUS2 (HDG2), as a key epidermal component promoting stomatal differentiation. HDG2 is highly enriched in meristemoids, which are transient-amplifying populations of stomatal-cell lineages. Ectopic expression of HDG2 confers differentiation of stomata in internal mesophyll tissues and occasional multiple epidermal layers. Conversely, a loss-of-function hdg2 mutation delays stomatal differentiation and, rarely but consistently, results in aberrant stomata. A closely related HD-ZIP IV gene, Arabidopsis thaliana MERISTEM LAYER1 (AtML1), shares overlapping function with HDG2: AtML1 overexpression also triggers ectopic stomatal differentiation in the mesophyll layer and atml1 mutation enhances the stomatal differentiation defects of hdg2. Consistently, HDG2 and AtML1 bind the same DNA elements, and activate transcription in yeast. Furthermore, HDG2 transactivates expression of genes that regulate stomatal development in planta. Our study highlights the similarities and uniqueness of these two HD-ZIP IV genes in the specification of protodermal identity and stomatal differentiation beyond predetermined tissue layers.

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Section: Hdg2 Is a Meristemoid-expressed Nuclear Proteinsupporting

confidence: 73%

Section: Research Articlementioning

confidence: 93%

Section: Research Articlementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Arabidopsishomeodomain-leucine zipper IV proteins promote stomatal development and ectopically induce stomata beyond the epidermis

et al. 2013

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“…During the initial patterning of the protoderm (Figure 17), from the 16 cell stage onwards, the expression of several genes are restricted to the central domain of the embryo, such as WUS and ZWILLE/PINHEAD (ZLL/PNH) (Moussian et al, 1998;Lynn et al, 1999) while others become preferentially expressed in the protoderm (Figure 17), such as PROTODERMAL FACTOR 1 and 2 (PDF1 and 2) (Abe et al, 1999;Abe et al, 2003) and AtML1 (Lu et al, 1996). PDF1/2 and AtML1 are expressed in the outer layer of the embryo (Figure 17) and subsequently in the (A) A stable morphogen gradient (blue) could specify radial cell fates.…”

Section: Separating Epidermal and Inner Cellsmentioning

confidence: 99%

Embryogenesis: Pattern Formation from a Single Cell

Capron

Chatfield

Provart

et al. 2009

The Arabidopsis Book

103

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During embryogenesis a single cell gives rise to a functional multicellular organism. In higher plants, as in many other multicellular systems, essential architectural features, such as body axes and major tissue layers are established early in embryogenesis and serve as a positional framework for subsequent pattern elaboration. In Arabidopsis, the apicalbasal axis and the radial pattern of tissues wrapped around it are already recognizable in young embryos of only about a hundred cells in size. This early axial pattern seems to provide a coordinate system for the embryonic initiation of shoot and root. Findings from genetic studies in Arabidopsis are revealing molecular mechanisms underlying the initial establishment of the axial core pattern and its subsequent elaboration into functional shoots and roots. The genetic programs operating in the early embryo organize functional cell patterns rapidly and reproducibly from minimal cell numbers. Understanding their molecular details could therefore greatly expand our ability to generate plant body patterns de novo, with important implications for plant breeding and biotechnology.

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Plant Embryogenesis (Zygotic and Somatic)

Harada

Belmonte

Kwong

2010

Encyclopedia of Life Sciences

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Zygotic embryogenesis in higher plants describes the developmental period in which the zygote undergoes a series of differentiation events, leading to the formation of a mature embryo. Establishment of the major embryonic organs and shoot and root apical meristems occur though partitioning events along the apical–basal axis, and many of these events are guided by the hormone auxin . Formation of the three embryonic tissue systems occurs along a radial axis perpendicular to the apical–basal axis. The mature zygotic embryo is generally developmentally arrested, metabolically quiescent and enclosed within maternal tissues of the seed. Somatic cells can be induced to divert from their normal fate and develop into embryos in a process termed somatic embryogenesis. Auxin and other plant hormones appear to play critical roles in inducing embryogenic competence. Zygotic and somatic embryogenesis represent parallel developmental programs in which cells acquire embryogenic cell fate and develop into mature embryos. Key Concepts: Embryo development can be divided into two phases: the morphogenesis phase in which the basic body plan of the embryo is established, and the maturation phase in which the embryo becomes tolerant of desiccation and accumulates storage macromolecules such as lipids, proteins and starch. During its development, the embryo is divided into distinct domains along its apical–basal and radial axes. Plant embryo formation represents a series of partitioning events in which organs and tissues are formed from larger domains. Cell fate within the embryo is largely dependent on the position of the cell within the embryo body. Plant cells are totipotent and have the ability to regenerate a fully differentiated organism. Somatic embryos follow similar developmental patterns to their zygotic counterparts, and they occur naturally or are induced in culture. Establishment of embryogenic competence occurs before the formation of the somatic embryo.

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Regulation of shoot epidermal cell differentiation by a pair of homeodomain proteins inArabidopsis

Abstract: the L1-specific gene expression (Abe et al., 2001). The L1 box is well-conserved within the promoter regions of all L1-specific

Cited by 336 publications

References 35 publications

Arabidopsishomeodomain-leucine zipper IV proteins promote stomatal development and ectopically induce stomata beyond the epidermis

Arabidopsishomeodomain-leucine zipper IV proteins promote stomatal development and ectopically induce stomata beyond the epidermis

Embryogenesis: Pattern Formation from a Single Cell

Plant Embryogenesis (Zygotic and Somatic)

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