Regulation of Wnt/β-catenin signaling by Marek’s disease virus in vitro and in vivo
Haiyin Xu,
Xihao Xu,
Huifeng He
et al.
Abstract:Marek’s disease virus (MDV) infection causes immunosuppression in the host, ultimately inducing tumor formation and causing significant economic losses to the poultry industry. While the abnormal activation of the Wnt/β-catenin signaling pathway is closely associated with the occurrence and development of tumors. However, the relationship between MDV and the Wnt/β-catenin pathway remains unclear. In this study, we found that the MDV RB1B strain, but not the MDV vaccine strain CVI988, activated the Wnt/β-cateni… Show more
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