Regulations of malaria in children with human immunodeficiency virus infection: A review

Abstract

This comprehensive review explores the intricate relationship between 2 major global health challenges, malaria and HIV, with a specific focus on their impact on children. These diseases, both endemic in sub-Saharan Africa, create a dual burden that significantly elevates the risk of morbidity and mortality, particularly in children with compromised immune systems due to HIV. The review delves into the complex mechanisms by which these infections interact, from heightened clinical malaria frequencies in HIV-infected individuals to the potential impact of antiretroviral therapy on malaria treatment. Different research engines were utilized in writing this paper such as Web of Science, Google Scholar, Pubmed Central, ResearchGate, and Academia Edu. To address this critical health concern, the study identifies and discusses various regulatory and treatment strategies. It emphasizes the importance of daily cotrimoxazole prophylaxis and insecticide-treated nets in preventing malaria in children with HIV. The potential of antiretroviral protease inhibitors and mRNA-based vaccines as innovative solutions is highlighted. Additionally, the study underscores the significance of climate data and artificial intelligence in improving diagnostics and drug development. Furthermore, the review introduces the concept of genetically modified mosquitoes as a novel approach to vector control, offering a promising avenue to protect HIV-positive individuals from mosquito-borne diseases like malaria. Through a comprehensive analysis of these strategies, the study aims to provide a foundation for policymakers, healthcare professionals, and researchers to develop effective regulations and interventions that reduce the dual burden of malaria and HIV in children, improving public health outcomes in endemic regions.

Concurrent management of HIV and malaria: A comprehensive review of strategies to enhance quality of life

“…ART used in HIV management may interact with antimalarial drugs, impacting their efficacy or leading to potential adverse effects. [ 28 ] Similarly, drugs used to treat malaria may have interactions with HIV medications, requiring careful consideration and monitoring to avoid adverse outcomes and ensure optimal treatment for both infections. [ 29 ]…”

Mental Health and Psychosocial Effects of natural disaster on HIV Patients

“…The combination of managing a chronic illness and enduring the traumatic aftermath of a disaster creates a complex and heightened psychological burden on this vulnerable population. [69][70][71][72][73][74] Natural disasters generate an array of stressors that exacerbate the existing challenges faced by HIV-positive individuals. The uncertainty surrounding access to essential medications, disrupted healthcare services, and the loss of stable living conditions can trigger acute stress, anxiety, and fear.…”

Prevention and Control of Infections in the University Community

“…Furthermore, the evolution of epidemiological traits and the range of disorders associated with various infectious diseases brought about new effects on population health within the framework of national and worldwide infectious disease epidemics. Infectious diseases have historically threatened the lives and health of children and adolescents [19][20][21]. Students in primary, junior, and senior high schools as well as the university community make up a unique group that has tight interpersonal interaction and high personnel population density, which makes them readily the source of infectious disease outbreaks in the absence of prompt control [22][23][24].…”