Regulatory factors of intracellular lysosomal activity associated with heterophagy and autophagy.

Analysis of the distribution of glycoconjugates in the digestive gland of the bivalve mollusc Mytilus galloprovincialis by conventional and lectin histochemistry

“…As shown by our results, mannose and/or glucose and GlcNAc residues are found in the limiting membrane of the apical lysosomal vesicles in digestive cells. The same glycoconjugates have been reported in the membrane of lysosomes in rat liver (Sakai et al 1990) where they might be involved in the protection of lysosomal membranes against the action of hydrolytic enzymes (Neiss 1984). On the other hand, galactose and mannose, and/or glucose residues are found in the contents of digestive cell lysosomes.…”

Cytochemical observation of nematolysosomes in rat corpus luteum during degeneration.

“…Moreover, we also found that there were swollen granule-like structures located on the end(s) or along the nematolysosomes. This description of the three-dimensional architecture of the lysosomal compartment agrees with previous in vivo studies employing cytochemical electron microscopy (3,4,14,27,28). From this study, it is apparent that nematolysosomes are a specialized intermediate form of the larger lysosomes, at the time when they translocate through the cytoplasm, particularly when the cells are stimulated by endocytic signals.…”

A Three-dimensional Observation of Acid Phosphatase-positive Structures in Rat Testis by High Voltage Electron Microscopy

“…On the other hand, the findings also indicate that the phagocytosis and intracellular processing of phagosomes in Sertoli cells could be stimulated by heating the testis, which had been reported causing injury of germ cells12), because an increasing of the number of lysosomes, particularly secondary lysosomes were observed in the cytoplasm. The fact that the nematolysosome was absent in the testicular cells indicates that nematolysosomes are not a ubiquitous structure of all the types of cells and tissues, although they have been found in several kinds of cells1-4, [10][11][13][14][16][17][18][19][20][21][22]. Meanwhile, in another study dealt with luteal cells (our unpublished data), the nematolysosomes were found to be increased in number after luteal cells naturally go to regressing.…”