Skin 3-D Models and Cosmetics Toxicity 2023
DOI: 10.1007/978-981-99-2804-0_9
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Regulatory Requirements for Safety/Toxicity Assessment of Cosmetics/Nanocosmetic Products: Challenges and Opportunities

Sana Sarkar,
Anuj Pandey,
A. B. Pant
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“…Even in ancient times, when all ingredients were natural, the toxicity of cosmetics was often high, especially when ingredients such as mercury and lead were used. In addition, there was ignorance about their effects [53]. Today, Regulation 1223/2009 for Cosmetics defines a "cosmetic product" as "any substance or mixture intended to come into contact with various external parts of the human body (skin, hair, scalp, nails, lips, and external genital organs) or with the teeth and the mucous membranes of the oral cavity, with the exclusive or main purpose of cleaning them, perfuming them, changing their appearance, and/or correcting body odors and/or protecting them or keeping them in good condition" [54].…”
Section: Cosmeticsmentioning
confidence: 99%
“…Even in ancient times, when all ingredients were natural, the toxicity of cosmetics was often high, especially when ingredients such as mercury and lead were used. In addition, there was ignorance about their effects [53]. Today, Regulation 1223/2009 for Cosmetics defines a "cosmetic product" as "any substance or mixture intended to come into contact with various external parts of the human body (skin, hair, scalp, nails, lips, and external genital organs) or with the teeth and the mucous membranes of the oral cavity, with the exclusive or main purpose of cleaning them, perfuming them, changing their appearance, and/or correcting body odors and/or protecting them or keeping them in good condition" [54].…”
Section: Cosmeticsmentioning
confidence: 99%