Rehab Rounds: Cognitive-Behavioral Therapy and Clozapine for Clients With Treatment-Refractory Schizophrenia

Pinto, Antônio Carlos Guedes; Pia, Silvestro La; Mennella, R.; Giorgio, Domenico Di; DeSimone, Luigi

doi:10.1176/ps.50.7.901

Cited by 131 publications

(85 citation statements)

References 9 publications

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“…[59][60][61][62][63][64][65][66][67] All these trials have involved providing CBT in conjunction with antipsychotic medication. CBT has been found to be superior to waiting list control, 59 structured activity and informal support, 60,61 routine care/treatment as usual (TAU), 62,66,67 supportive counselling and routine care, 63 supportive therapy in combination with clozapine, 64 befriending (BF) 65 and supportive psychotherapy (SP). 66 Table 60 (Appendix 1) shows the basic design, participants, outcomes and follow-up periods of trials of RCTs involving CBT for patients diagnosed with schizophrenia or similar condition, who had been followed up for longer than 12 months post-randomisation.…”

Section: Schizophreniamentioning

confidence: 99%

“…These figures were chosen in order to make meaningful comparisons with the three main clinical trials published in this area. [62][63][64] Although both figures are somewhat arbitrary, most clinicians with experience of chronic schizophrenia are likely to regard a 25% improvement as being worthwhile and a 50% improvement as representing an important clinical change.…”

Section: Percentage Change In Panss Scores For Psychosis Studies (Trimentioning

confidence: 99%

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Long-term outcome of cognitive behaviour therapy clinical trials in central Scotland

Durham

Chambers²,

Power³

et al. 2005

Health Technol Assess

110

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Section: Schizophreniamentioning

confidence: 99%

Section: Percentage Change In Panss Scores For Psychosis Studies (Trimentioning

confidence: 99%

Long-term outcome of cognitive behaviour therapy clinical trials in central Scotland

Durham

Chambers²,

Power³

et al. 2005

Health Technol Assess

110

View full text Add to dashboard Cite

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“…Lynch et al also claimed that rater bias has led to inflated estimates of CBTp efficacy, based on the observation that two small (N=37-40) non-blind studies (Drury et al, 1996;Pinto, La Pia, Mannella, Domenico and DeSimone, 1999) reported relatively larger effects than those employing rater-masking. Although non-blindness is a well-known source of bias (Schulz, Chalmers, Hayes and Altman, 1995), Lynch et al did not consider alternative explanations for the differences, such as publication bias, small sample effects, regression to the mean, exclusion of participants from the analysis (Drury et al, 1996), or the additional interventions received by the CBT group participants (Drury et al, 1996;Pinto et al, 1999).…”

Section: Previous Meta-analyses Lynch Et Al (Lynch Laws and Mckennamentioning

confidence: 99%

“…Although non-blindness is a well-known source of bias (Schulz, Chalmers, Hayes and Altman, 1995), Lynch et al did not consider alternative explanations for the differences, such as publication bias, small sample effects, regression to the mean, exclusion of participants from the analysis (Drury et al, 1996), or the additional interventions received by the CBT group participants (Drury et al, 1996;Pinto et al, 1999). Indeed, two blind studies reported even larger effects than the non-blind studies, but these were excluded by Lynch et al because they were too small (Levine, Barak and Granek, 1998;Turkington and Kingdon, 2000).…”

Section: Previous Meta-analyses Lynch Et Al (Lynch Laws and Mckennamentioning

confidence: 99%

Cognitive behavioural therapy for psychosis: rationale and protocol for a systematic review and meta-analysis

et al. 2013

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Background: Cognitive behavioural therapy (CBT) is a recommended treatment for people with psychosis, with meta-analyses showing important benefits when compared to treatment as usual (TAU). However, there has been growing debate as to whether CBT has specific benefits over and above those attributable to less intensive psychosocial interventions, such as befriending and supportive counselling. Recent meta-analyses examining this question have suffered from various difficulties including potential bias and error. After detailing these problems, we present a protocol for a new review.

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“…Or, les 7 études retenues ont toutes introduit la TCCp en phase aiguë et 4 d'entre elles offraient plus d'une séance par semaine 6,7,10,12 . Aussi, parmi les études de TCCp sur les symptômes persistants qui rapportent un nombre moyen de participations aux séances supérieur ou égale 18 séances, toutes ont offert la TCCp en inter-épisode à raison d'une séance par semaine [36][37][38][39] . Ensemble, ces résultats suggèrent que la participation aux séances de thérapie soit favorisée par un protocole qui introduit la TCCp en inter-épisode (plutôt qu'en phase aiguë) et (ou) qu'elle soit favorisée par un protocole d'une fréquence de rencontres prédéterminée à 1 fois/semaine (plutôt qu'à 2 fois/semaine).…”

Section: Applicabilité De La Tccpunclassified

La thérapie cognitivo-comportementale des psychoses en début d'évolution: étude ouverte en milieu clinique

et al. 2011

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Rehab Rounds: Cognitive-Behavioral Therapy and Clozapine for Clients With Treatment-Refractory Schizophrenia

Cited by 131 publications

References 9 publications

Long-term outcome of cognitive behaviour therapy clinical trials in central Scotland

Long-term outcome of cognitive behaviour therapy clinical trials in central Scotland

Cognitive behavioural therapy for psychosis: rationale and protocol for a systematic review and meta-analysis

La thérapie cognitivo-comportementale des psychoses en début d'évolution: étude ouverte en milieu clinique

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