The aim was to explore the fracture-behavior, survival and marginal-microgaps within the root-canal of immature anterior teeth restored with different fiber-reinforced post-core composites (FRCs). 180 bovine-incisors were randomly divided into 6 groups (n = 30). One group served as control (group 6). The rest of the teeth were prepared to an internal diameter of 1.6 mm and the apex was sectioned. After application of an MTA-plug, teeth were restored with FRC materials: Group 1: Bioblock technique with short fiber-reinforced composite (SFRC); Group 2: Bioblock technique with flowable SFRC; Group 3: Individually-made FRC post; Group 4: Conventional FRC post; Group 5: dual-cure core build-up composite. After restorations were completed, teeth (n = 5/group) were sectioned and then stained. Specimens were viewed under a stereo microscope and the percentage of microgaps within the root-canal was calculated. Fatigue-survival was measured using a cyclic-loading testing machine in the rest of the specimens. Flowable SFRC application in the root-canal (Group 2) did not differ from intact-teeth regarding fatigue-survival (p > 0.05). The rest of the groups produced significantly lower survival (p < 0.05) compared to intact-teeth. Post/core restorations made from conventional FRC post (Group 4) exhibited a high number of microgaps (38.3%) at the examined interphase in the root-canal. The restoration of immature incisors with the use of flowable SFRC as post-core material displayed promising performance in a matter of fatigue-resistance and survival.