Explor Cardiol 2024
DOI: 10.37349/ec.2024.00027
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Reinforcing the aneurysmal aorta by additional layering: old and new strategies to prevent rupture

Traian V. Chirila

Abstract: Adventitial crosslinking is a method in current investigational stage for preventing the rupture of aortic aneurysms. It is based on the photochemical crosslinking of adventitial collagen by exposure to ultraviolet A radiation. Essentially, an adventitial top layer is generated that displays enhanced mechanical properties and imparts additional strength and stiffness to the aneurysmal wall. Looking back upon the history of aortic surgery during 1940s, the aortic film wrapping, then dubbed “cellophane wrapping”… Show more

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