Rekonstruktion von Segmentdefekten der langen Röhrenknochen

Militz, med. Matthias; Gabler, Carolin; Mauck, Josephine; Miethke, Christoph; Bialas, Robert; Bühren, V.; Mittelmeier, Wolfram; Öhlbauer, M.; Bader, Rainer

doi:10.1007/s10039-015-0096-3

Cited by 2 publications

(1 citation statement)

References 35 publications

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“…After a consolidation period, a vascularized pediculated bone graft with a similar inner diameter as the recipient bone was available, and transplantation of the graft could be performed [28]. Compared to the callus distraction method, this procedure avoids the pin tract infections associated with external fixation and enables a shorter treatment duration [29]. In order to demonstrate the feasibility of this procedure, a completely implantable medical device for fibula expansion (Figure 2) in a domestic pig model was developed and is characterized in the present study.…”

Section: Methodsmentioning

confidence: 99%

Novel Concept for the Expansion of the Fibula Bone as an Autologous Bone Graft: Experimental Tests on an Animal Implant Prototype—In Memoriam Volker Buehren

Militz,

Buehren,

Miethke

et al. 2024

Surgical Techniques Development

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The current reconstructive surgical procedures implemented after the resection of extended bone segments are associated with high complication rates and long-term treatments. By transplanting an autologous, vascularized and stabilized bone segment, these challenges can be managed. Thus, we propose a novel procedure to expand the currently available autologous bone grafts to the dimensions of the recipient bone using an implantable device. The objective of the present study was to characterize the feasibility of developing an implant prototype for fibula expansion in an in vitro model using a porcine fibula. A balloon catheter, as the part of the implant responsible for expansion, was proven to expand while being periodically filled with sodium chloride. Therefore, the expansion of the balloon catheter was analyzed in an experimental test setup with a 3D-printed porcine fibula with a closure film simulating callus formation to simulate the in vivo situation. Our experimental testing proved the successful expansion of the porcine fibula by the balloon catheter. Hence, the feasibility of the concept for subsequent animal testing was confirmed.

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Section: Methodsmentioning

confidence: 99%