Relações Clínicas Dos Contraceptivos Orais No Curso Da Doença Periodontal

Moura, M.; Moura, Adolpho Marlon Antoniol de; Pessanha, Aline Manhães; Miquilito, Diogo Elias

doi:10.18571/acbm.190

Cited by 1 publication

(1 citation statement)

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“…Women are more susceptible to hormonal changes, especially during puberty, pregnancy, and menopause [ 5 ]. These hormonal changes can induce an immunological response in the oral microbiota and cause vascular and gingival changes that may contribute to increased gingival inflammation [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

MMP-8 in Periodontal Sites of Postpartum and without-Any-Pregnancy Women

Lima,

Calado,

Pereira

et al. 2024

IJERPH

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The hypothesis that physiological changes in women can affect periodontal tissues is the subject of this study, and inflammatory markers such as matrix metalloproteinase-8 can measure susceptibility to inflammation. The study aimed to analyze MMP-8 levels in periodontal sites of postpartum women and women without a history of pregnancy, comparing health parameters and periodontal disease. This is a case–control study with 40 participants, 20 cases (women in the postpartum period) and 20 controls (women without any pregnancy), who underwent clinical periodontal examination and the collection of crevicular gingival fluid. The ELISA test was used to detect MMP-8 levels. Postpartum women had worse periodontal parameters, such as bleeding index on probing, number of sites with CAL ≥ 3, and fewer teeth present. In the group of women without a history of pregnancy, a significantly lower MMP-8 level was observed in healthy sites and a higher one was observed in periodontal pockets (p < 0.01). In contrast, in postpartum women, MMP-8 levels were elevated in both healthy sites and periodontal pockets (p > 0.01). The MMP-8 levels in gingival fluid appear to be related to periodontal clinical parameters and may be a possible marker of enzymatic changes involved in periodontal tissue destruction in postpartum women.

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Section: Introductionmentioning

confidence: 99%