Relapse of Tourette Syndrome with Clozapine in a Patient of Paranoid Schizophrenia

Abstract

Tourette syndrome (TS) is characterized by multiple motor and vocal tics and is commonly associated obsessiveCompulsive Disorder (OCD). Comorbidity between TS and schizophrenia has been less commonly described. In this case report a case of schizophrenia with comorbid TS is described in which symptoms of TS relapsed when the patient was started on clozapine. Exacerbation of TS with clozapine has been reported in few case reports in the literature. Our case highlights the fact that clozapine should be used with caution in patients with schizophrenia who have tic disorder.