Relapsing advanced metatypical basal cell carcinomas (MTBCC) of the face: Surgical modalities

Tchernev, Georgi; Chokoeva, Anastasiya Atanasova; Penev, P; Ananiev, Julian; Nowak, Andreas; Bayyoud, Yousef; Philipov, Stanislav; Cardoso, JC; Wollina, Uwe

doi:10.1007/s10354-014-0314-9

Cited by 4 publications

(11 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinical differentiation of BSC and BCC is impossible owing to their clinical similarity [8]. Dermoscopic patterns may facilitate early diagnosis and accurate management, which comprises BCC-related criteria, as well as features that are known to characterize invasive SCC [9].…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, histopathological examination is mandatory before primary treatment [8]. Histologically BSC is classified in two type-intermediate and mixed [8].…”

Section: Discussionmentioning

confidence: 99%

“…Histologically BSC is classified in two type-intermediate and mixed [8]. The first one shows areas typical for both BCC and SCC, transitional zones and tumor islets found together.…”

Section: Discussionmentioning

confidence: 99%

“…Histological examination of the surgical specimen with a margin of 6 mm, revealed an infiltrating tumour with a mixed basal and spindle cell pattern with disease-free resection margins ( Figure 7 and Figure 8). Immunohistochemi- able) may provide additional data for a more accurate diagnosis, typically showing strong positivity for keratins 17 and 8 in BCC, and 6 to 8 times decreased intensity of staining in BSC [8].…”

Section: Case Reportmentioning

confidence: 99%

“…In addition, BSC also shows a more frequent presence of atypical mitotic figures, such as multipolar or tripolar mitoses [8].…”

Section: Case Reportmentioning

confidence: 99%

See 4 more Smart Citations

Basosquamous Carcinoma: Report of Two Cases and Review of Literature

Ch¹,

Baybay²,

Elmahi³

et al. 2018

Int J Cancer Clin Res

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

“…Therefore, histopathological examination is mandatory before primary treatment [8]. Histologically BSC is classified in two type-intermediate and mixed [8].…”

Section: Discussionmentioning

confidence: 99%

“…Histologically BSC is classified in two type-intermediate and mixed [8]. The first one shows areas typical for both BCC and SCC, transitional zones and tumor islets found together.…”

Section: Discussionmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

“…In addition, BSC also shows a more frequent presence of atypical mitotic figures, such as multipolar or tripolar mitoses [8].…”

Section: Case Reportmentioning

confidence: 99%

See 3 more Smart Citations

Basosquamous Carcinoma: Report of Two Cases and Review of Literature

Ch¹,

Baybay²,

Elmahi³

et al. 2018

Int J Cancer Clin Res

View full text Add to dashboard Cite

Undermining plastic surgery as a possible option for treating basal cell carcinoma of the forehead

Tchernev

Pidakev

Lozev

et al. 2017

Wien Med Wochenschr

Self Cite

View full text Add to dashboard Cite

Basal cell carcinoma (BCC) is the most common cutaneous cancer. Although most cases can be cured with simple surgical procedures and are associated with a good prognosis, a minority of BCCs may pose significant therapeutic challenges. This occurs mostly in cases of so-called advanced BCC, which a loosely defined term that encompasses locally advanced lesions and tumors with metastatic spread. Treatment of these cases is often complex and sometimes may need combinations of therapeutic modalities, including surgery, radiotherapy and/or targeted therapy directed towards sonic hedgehog (SHH) signaling pathways, such as vismodegib. We herein present the case of a 74-year-old man presenting with a large basal cell of the forehead evolving for more than 7 years. The patient underwent excision of the lesion with clear surgical margins. Reconstruction of the defect was performed after extensive undermining of the skin allowing subsequent direct closure with a simple suture, which resulted in an acceptable cosmetic outcome. We discuss the potential advantages, disadvantages, and applicability of this relatively simple surgical maneuver in the reconstruction of defects resulting from excision of considerably large cutaneous tumors.

show abstract

Comparative Analysis of the Applicability of Island Flap in Primary and Recurrent Basal Cell Carcinomas of Similar Localization

Tchernev¹,

Temelkova²,

Mangarov³

et al. 2018

Open Access Maced J Med Sci

Self Cite

View full text Add to dashboard Cite

BACKGROUND:Basal cell carcinoma belongs to non-melanoma skin cancers and is the most prevalent neoplasia that shows a tendency to increase over the last few decades. It occurs most often in skin areas exposed to sunlight. It is characterised by slow progression, low tendency to metastasising and good prognosis when the right choice of treatment has been made. The difficulty in the treatment of basal cell carcinomas is determined by their localisation and puts to the test the aesthetic potential of dermatosurgeons. Complete surgical excision is the standard approach in most uncomplicated cases. In relapsing basal cell carcinoma or carcinoma with aggressive or unfavourable histopathological characteristics, the clinician faces the dilemma of identifying the most appropriate method of treatment. To find the decision, help comes from the individualisation of each case and the related risk factors.CASE REPORT:Two cases of basal cell carcinoma of similar localisation are presented, where the carcinomas are removed using island flaps. In spite of the desire to observe the recommended field of surgical security (by the desire for the ultimate esthetic effect for the patient), one of the tumours was not completely removed, and as an alternative, reoperation was proposed using Mohs micrographic surgery (MMS).CONCLUSION:The choice of a surgical technique, which would guarantee a better outcome and could be applied depending on the individual risk factor in each patient, is discussed.

show abstract

Relapsing advanced metatypical basal cell carcinomas (MTBCC) of the face: Surgical modalities

Cited by 4 publications

References 22 publications

Basosquamous Carcinoma: Report of Two Cases and Review of Literature

Basosquamous Carcinoma: Report of Two Cases and Review of Literature

Undermining plastic surgery as a possible option for treating basal cell carcinoma of the forehead

Comparative Analysis of the Applicability of Island Flap in Primary and Recurrent Basal Cell Carcinomas of Similar Localization

Contact Info

Product

Resources

About