Relapsing peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis due to Corynebacterium aquaticum

Clinical microbiology of coryneform bacteria

“…Remarkably, "C. aquaticum" ranks third (after C. diphtheriae and L. monocytogenes) in the Hollis-Weaver charts with regard to the number of isolates tested for each taxon (204), but this may be due to referral bias. It has been reported to be an agent of meningitis (24), bacteremia (227,295,453), CAPD peritonitis (57,297), and UTI (426) and has caused pseudobacteremia due to contamination of blood collection tubes as well (352). However, at least some of these case reports are doubtful from a diagnostic standpoint, as none of them included the above biochemical tests and/or chemotaxonomic investigations (especially detection of DAB), so that it remains unclear whether the strains were actually "C. aquaticum" or Aureobacterium spp.…”

Relapsing peritonitis with Corynebacterium aquaticum in a boy receiving automated peritoneal dialysis

“…It has been reported in association with neonatal meningitis and urinary tract infection, septicemia in an elderly patient with diabetes and septic shock in an human immunodeficiency virus (HIV)-infected patient [3][4][5][6]. To date, C. aquaticum peritonitis has been reported in only three continuous ambulatory peritoneal dialysis (CAPD) adult patients [7][8][9]. Here, we describe a boy with relapsing peritonitis caused by C. aquaticum who had received automated peritoneal dialysis (APD).…”

“…Corynebacterium aquaticum was first reported as a cause of bacterial peritonitis in a CAPD patient due to diabetic nephropathy in 1986 [7]. Since then, there have been three case reports of PD-related peritonitis in adults, with all patients eventually requiring the removal of the PD catheter because of persistent or recurrent infections [7][8][9].…”

“…Since then, there have been three case reports of PD-related peritonitis in adults, with all patients eventually requiring the removal of the PD catheter because of persistent or recurrent infections [7][8][9]. The rationale for intractable peritonitis caused by C. aquaticum in the presence of adequate antibiotic therapy may result from its ability to form a biofilm around the catheter [9].…”

Outcome of an Opportunistic Infection after Polymicrobial Peritonitis in an HIV-Infected Patient Treated with Peritoneal Dialysis

“…Although Corynebacteria are generally contaminants, group JK has been associated with severe infections, sepsis and soft tissue infections, particularly in immunosuppressed patients. Corynebacterium aquaticum, known as a water contaminant, was reported as causing peritonitis in patients treated with CAPD [14,15]. Group JK can be distinguished from other Corynebacterium by its slow growth, distinctive biochemical reactions and multiple resistance to antibiotics.…”