Related cardiometabolic factors and prevalence of low HDL-cholesterol levels and atherogenic dyslipidemia. SIMETAP-AD study

Ruiz‐García, Antonio; Arranz-Martínez, Ezequiel; García-Fernández, María Eugenia; Cabrera-Vélez, Roberto; García-Pliego, Rosa A.; Morales-Cobos, Luis Enrique; Sanz-Pozo, Blanca; Gómez-Díaz, Esther; Rodríguez-de-Mingo, Enrique; Rico-Pérez, María R.; Migueláñez-Valero, Alfonso; Calderín-Morales, M.P.; Sandín-de-Vega, Eloína; Hombrados-Gonzalo, María P.; Luna-Ramírez, Sonia; Sánchez-Ramos, María C.; Mora-Casado, Cristina; Moreno-Muñoz, María S.; González-Escobar, Paloma; Ruiz-Díaz, Lourdes; Caballero-Ramírez, Nuria; Zamora-Gómez, María M.; Iturmendi-Martínez, Nerea; Holgado-Catalán, María S.; Álvarez-Benedicto, Rebeca; Sanchidriá-Fernández, Pedro L.; Benito-Alonso, Elena; Fernández-Vicente, Teresa; Hernández-López, Rosa M.; Doria-Carlin, Norma Alejandra; Frías-Vargas, Manuel J.

doi:10.1016/j.artere.2020.12.003

Cited by 2 publications

(3 citation statements)

References 27 publications

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“…This response is consistent with epidemiological data published in the IBERICAN study, conducted among PC physicians in Spain [26], and with other surveys, such as Plana et al, where physicians prioritized DM and CVD, without mentioning obesity [27]. The responses provided seem not only to be in line with reality and with published data, but also to be sincere, since they acknowledge that the most widely used strategy is moderate-intensity statins, as in other developed countries [28]; this could justify the low degree of control of patients with dyslipidemia in our country [29]. We consider that, with the availability of new therapies, it is very important to know the degree of control of dyslipidemia bearing in mind the new targets, to reveal the actual situation and to take measures to improve the cardiovascular prognosis in our population [30].…”

Section: Discussionsupporting

confidence: 71%

“…Another reason that could explain this strategy is the underestimation of the patients' CVR on the part of their physicians, as observed in other surveys [37], which, as stated above, cannot be accepted in view of our results. A third explanation is that the inertia might have been the result of an overestimation of the patients' degree of control; therefore, there was no perceived need to intensify the treatment, whereas the reality is very different with LDL control figures lower than 25% [15,29,38].…”

Section: Discussionmentioning

confidence: 99%

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Cardiovascular Risk in Patients with Dyslipidemia and Their Degree of Control as Perceived by Primary Care Physicians in a Survey—TERESA-Opinion Study

Pallarés-Carratalá

Barrios

Fierro-González³

et al. 2023

IJERPH

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Objective: The aim of this study was to evaluate, through a survey, the opinion of primary care (PC) physicians on the magnitude of dyslipidemia and its degree of control in their clinical practice. Materials and methods: An ecological study was carried out, in which the physicians were invited to participate by means of an online letter. Data were collected at a single timepoint and were based only on the experience, knowledge, and routine clinical practice of the participating physician. Results: A total of 300 physicians answered the questionnaire and estimated the prevalence of dyslipidemia between 2% and 80%. They estimated that 23.5% of their patients were high-risk, 18.2% were very high-risk, and 14.4% had recurrent events in the last 2 years. The PC physicians considered that 61.5% of their patients achieved the targets set. The participants fixed the presence of side-effects to statins at 14%. The statin that was considered safest with regard to side-effects was rosuvastatin (69%). Conclusions: PC physicians in Spain perceive that the CVR of their patients is high. This, together with the overestimation of the degree of control of LDL-C, could justify the inertia in the treatment of lipids. Moreover, they perceive that one-sixth of the patients treated with statins have side-effects.

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Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 99%

Cardiovascular Risk in Patients with Dyslipidemia and Their Degree of Control as Perceived by Primary Care Physicians in a Survey—TERESA-Opinion Study

Pallarés-Carratalá

Barrios

Fierro-González³

et al. 2023

IJERPH

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“…The deprivation level according to the MEDEA (socioeconomic status) index [ 17 ] was also collected in quintiles with the primary care centre as a unit of analysis and with the first quintile as the least deprived population. Low HDL was defined as < 40 mg/dl for men and < 50 mg/dl for women, while atherogenic dyslipidaemia was defined as the presence of low HDL cholesterol and triglycerides ≥ 150 mg/dl [ 18 ].…”

Section: Methodsmentioning

confidence: 99%

Epidemiology of the first-ever cardiovascular event in people with type 1 diabetes: a retrospective cohort population-based study in Catalonia

Giménez-Pérez

Viñals

Mata-Cases

et al. 2023

Cardiovasc Diabetol

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Background Knowledge of the characteristics of first-ever cardiovascular events in type 1 diabetes may impact primary prevention strategies. This study describes the first-ever manifestation of cardiovascular disease (CVD) in patients with type 1 diabetes (T1D) in Catalonia (Spain) and evaluates differences according to age and sex. Methods Retrospective cohort study of patients with T1D > 30 years without CVD before 2010 registered in the SIDIAP database. The occurrence of a first cardiovascular event up to the end of 2016, the type of CV event and associations with baseline characteristics were analysed. Results Of 8412 patients, 884 suffered a first CV event (incidence rate 1.62 per 100 persons-years). Overall, peripheral vascular disease (39.5%) was the most frequent event. We observed a higher proportion of heart failure in women (21.7%) than in men (10.1%). In women, heart failure was the most frequent event in those > 65 years (40.5%). Decreased glomerular filtration rate (hazard ratio [HR] 5.42 [95% CI 4.32;6.80]), elevated albumin/creatinine ratio (HR 3.39 [95% CI [2.47;4.66], microvascular complications (HR 3.27 [95% CI 2.85;3.75]), and hypertension (HR 3.21 [95% CI [2.80;3.67]) were most strongly associated with a first CV event. HbA1c > 7.0% was associated with incident CVD only in patients aged < 55/60 years. Conclusions Peripheral artery disease in the whole cohort, and heart failure in elder subjects are the most frequent first-ever CVD events in T1D in our region. These findings deserve to be taken into account when considering primary prevention measures and when estimating CV risk in people with T1D.

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Related cardiometabolic factors and prevalence of low HDL-cholesterol levels and atherogenic dyslipidemia. SIMETAP-AD study

Cited by 2 publications

References 27 publications

Cardiovascular Risk in Patients with Dyslipidemia and Their Degree of Control as Perceived by Primary Care Physicians in a Survey—TERESA-Opinion Study

Cardiovascular Risk in Patients with Dyslipidemia and Their Degree of Control as Perceived by Primary Care Physicians in a Survey—TERESA-Opinion Study

Epidemiology of the first-ever cardiovascular event in people with type 1 diabetes: a retrospective cohort population-based study in Catalonia

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