“…Health care systems are complex adaptive systems (CAS) with many agents (patients, providers, insurances, government agencies, researchers) engaged in prevention, diagnosis, and treatment (Krubiner & Hyder, 2014;Rouse, 2008); Changing such a system requires a systemic approach, that is, any potential innovation needs to be analysed with respect to related requirements, impacts, and obstacles: Related innovations (RI) mean that in order to succeed, one focal innovation affects and is affected by (or even requires the invention of) a number of other innovations (Hauerwaas & Weisenfeld, 2017). Influencing each other and the whole system, RI are systemic innovations that generate system change (e.g., Mulgan, 2013).…”