Background & aim: One of the important fields in youth health is the psychological dimensions requiring attention and prevention of disorders such as anxiety. Exposure to death and anxiety of the inevitability of death are universal psychological quality for human beings. The aim of the present study was to determine the relationship between God Image and Self-Actualization with death Anxiety among the university students. Methods: This study was a descriptive correlational study including 206 students resided in dormitories of Tehran University. Subjects were selected by accessible sampling method. Data collection tools were Death Anxiety Scale (DAS), Self-Actualization Scale (SISA), and Index of God Image (GI). Data were analyzed by the Pearson correlation coefficient and multiple regressions using SPSS 16 software. Results: The results of the study showed that there was a significant correlation between the image of God and the self-actualization (p<0.01). The components of the image of God (except the challenge component) increased by increasing individuals self-actualization. Also, there was a reverse correlation between death anxiety and components of the image of God (except the challenge component) with self-actualization (p<0.01). The results of multiple regression showed that the image of God and self-actualization can be used to predict the students' death anxiety. Conclusion: It concluded that God image and self-actualization could be used to explain the death anxiety among students. Improving the image of God and self-actualization in students can reduce the anxiety of death in them.