Relation between premorbid adjustment, duration of untreated psychosis and close interpersonal trauma in first‐episode psychosis

Abstract

Close interpersonal trauma before the age of 18 is associated with poorer premorbid adjustment and a longer duration of untreated psychosis. This may indicate that traumatic experiences delay help-seeking behaviour.

Potentially traumatic events in youth with and at clinical high risk for psychosis

“…CHR and PD participants also reported more direct, interpersonal forms of PTEs (ie, Sexual Abuse , Physical Abuse , Victim of a Violent Crime ) relative to TD participants. While larger samples sizes are necessary to examine specific types of trauma as they relate to psychosis risk, these results align with previous work highlighting the strong association between interpersonal traumatic events and the development of psychotic symptoms, particularly among victims who maintain a close relationship with the perpetrator (Gibson, Alloy, & Ellman, ; Haahr et al, ). Among the CHR group, 63.2% reported at least 1 previous PTE, less than the 86.8% found in Kraan et al's meta‐analysis ().…”

Premorbid adjustment amongst outpatients with schizophrenia in a Nigerian psychiatric facility

“…Of all the variables investigated, poor premorbid adjustment was significantly associated with male gender. Studies 14 , 45 , 46 , 47 have shown that males with schizophrenia tend to have poorer premorbid functioning than their female counterparts. Other authors 19 have also posited that males experience more decline in their premorbid functioning over the epoch ages.…”

Intersecting disadvantage: Unpacking poor outcomes within early intervention in psychosis services

“…Longer duration of untreated psychosis (DUP) has also been linked to poorer medium-long term outcomes (Marshall et al, 2005), though a recent meta-analysis suggests that correlations are small and leave substantial variability unexplained (Penttilä, Jääskeläinen, Hirvonen, Isohanni, & Miettunen, 2014). Childhood trauma and community disadvantage have also been strongly linked not only to increased risk for developing psychosis but also to initial help-seeking pathways and outcomes following onset (Cotter, Kaess, & Yung, 2015;Haahr et al, 2016;Stain et al, 2014). Outcomes and engagement in services are strongly linked, and a recent meta-analysis of engagement predictors found consistent evidence for DUP, symptom severity, insight, substance abuse and family involvement (Doyle et al, 2014).…”