Relation of ABO Blood Group on Fibrinogen Levels and Platelet Count in Apparently Healthy Sudanese Subjects at Khartoum state, 2022

Abstract

No diseases are known to result from the lack of expression of ABO blood group antigens, but the susceptibility to a number of diseases has been linked with a person's ABO phenotype. A cross sectional study conducted at research laboratory of Gharb El-Niel College from May to August 2022, to estimate the relation of ABO blood group on fibrinogen levels and platelet count in apparently healthy Sudanese subjects. For the A positive blood group there was significant decreased in the fibrinogen level when compared with the B⁺, O⁺ and O⁻ blood group, and in significant differences with the AB⁺ and A⁻. For the platelets counts; there was significant increased with AB⁺ and in significant differences with other blood groups, for the B⁺; there was significant decreased in the fibrinogen level when compared with other blood groups, however in the platelets count there was insignificant differences in all blood grouping except the O⁺. In addition, there was significant decreased in the fibrinogen level in O⁺ when compared with the AB⁺ and A⁻. AB⁺ when compared with the O⁻, and A⁻ when compared with O⁻. Regarding the platelets count there was significant differences when O⁺ blood group compared with AB⁺, and AB⁺ when compared with the A⁻ and O⁻. There were insignificant differences when the fibrinogen level and platelets count compared with the age and gender. Finally, there was a clear significant decreased in the fibrinogen levels and platelets count among the individuals with different ABO blood group.
 Keywords: ABO blood group, fibrinogen, platelets, phenotype, coagulometer.