A school-based screening with anthropometric and blood pressure (BP) measurements was performed in adolescents aged 12-17 years in the island of Samos, . In multivariate analysis, BMI, male gender and age, but also modifiable factors (lack of physical activity, breakfast skipping, smoking and low milk consumption) were associated with increased BP levels in the study population. These data indicate that further to BMI, other factors such as adverse lifestyle and dietary habits appear to be associated with elevated BP levels in adolescents. Moreover, rising trends seem to characterize the prevalence of high BP.