Relations Between Occurrence of the Risk of Food-Drug Interactions and Patients’ Socio-Demographic Characteristics and Selected Nutrition Habits

Abstract

Key words: food-drug interactions, knowledge on drugs interactions with foodThe objective of the study was to investigate the patients' exposure to food-drug interactions, and to analyse the main factors leading to a risk of interactions in the examined patients. A high (62.4%) risk of food-drug interactions incidence, which may cause various complications in therapy, was found in the study. The majority of patients (52.8%) were not aware that the timing of drug intake in relation to meals may affect treatment.High exposure to food-drug interactions in patients results generally from their lack of awareness of such interactions and of their effects. The results of the study show that educating patients, physicians, dieticians and nurses on the impact of food on the effects of drugs is necessary to mitigate pharmacotherapy complications.

Survey of adherence to time standards to prevent food and drug interaction in the hospitalized patients

“…In their study of food and drug interactions, Lopes et al asserted that 13% of the reported food and drug interactions were related to aspirin (acetyl salicylic acid (anti-inflammatory drug)), 10 cases (17%) to captopril (cardiovascular drug), and 18 cases (30%) to spironolactone, which had the highest number of interactions among the other studied drug categories. Their results on interactions of captopril are consistent with the present study findings [5]. In their study of food and drug interactions, Leibovitch et al reported interactions among cardiovascular, psychoactive, antibiotic, endocrine, gastrointestinal, and respiratory medications.…”

“…Health care providers can prevent food and drug interactions and complications by careful drug selection and counseling for older patients [14]. The results of the study by Lopes on the evaluation of food and drug interactions were consistent with those of the present study and revealed that from the total food and drug interaction cases, 53% were related to cardiovascular drugs, 22% to antiinflammatory drugs, 18% to diuretic drugs, and 7% to gastrointestinal drugs [5]. Abbasi Nazari et al reported frequent incorrect use of hydrochlorothiazide, captopril, and gemfibrozil, and 44% of drug administration was incorrect in relation to meals in their study.…”

“…However, the association between drugs and food can lead to undesirable interactions, resulting in an increase or decrease in the efficacy of the drug and food [5]. Many people mistakenly believe that there is always no problem with simultaneous consumption of drugs and foods and they consider it safe; however, the interactions between foods and medications can have a profound effect on the success of the treatment and the side effects of many medications.…”

“…The nurse is responsible for the proper administration of medications, which can include preparing, controlling, and administering the medications, updating their knowledge of medications, monitoring the effectiveness of treatment, reporting the side effects, and training patients about their medications [9]. The results of Jarosz and Wolnicka's study showed that 62.4% of the patients consumed medications incorrectly related to the meal [5]. Similarly, in the study by Abbasi Nazari et al, several mistakes were found in medication consumption, especially in wards with high rate of medication consumption [7].…”

“…Similarly, in the study by Abbasi Nazari et al, several mistakes were found in medication consumption, especially in wards with high rate of medication consumption [7]. Moreover, Lopes et al conducted a study to assess the relationship between food and drug interactions in Brazil, and their results showed that a high rate of interaction between food and drug is possible [5]. Aman et al, conducted studies on "Food and Drug Interactions in Pakistan in 2010 " and their results indicated that accurate compliance with medication consumption standards was required [11].…”