Relations of Platelet Indices with Endometrial Hyperplasia and Endometrial Cancer

Karateke, Atilla; Kaplanoğlu, Mustafa; Baloğlu, Ali

doi:10.7314/apjcp.2015.16.12.4905

Cited by 32 publications

(29 citation statements)

References 16 publications

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“…16 In our study, we found that preoperative MPV measurements let counts, and hemoglobin levels and they reported that there was no significant difference between groups. 17 In our study, we found the lowest hemoglobin and hematocrit levels in endometrial carcinoma group. investigated.…”

Section: Discussionsupporting

confidence: 52%

“…In the study performed by Karateke et al in patients with endometrial carcinoma and endometrial hyperplasia, the highest MPV values were determined in the endometrial carcinoma group and the lowest MPV values were determined in the control group. Karateke et al compared the groups with respect to white blood cell counts, platelet counts, and hemoglobin levels and they reported that there was no significant difference between groups . In our study, we found the lowest hemoglobin and hematocrit levels in endometrial carcinoma group.…”

Section: Discussioncontrasting

confidence: 42%

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Evaluation of complete blood count parameters to predict endometrial cancer

Abide

Ergen

Çöğendez

et al. 2018

Clinical Laboratory Analysis

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Section: Discussionsupporting

confidence: 52%

Section: Discussioncontrasting

confidence: 42%

Evaluation of complete blood count parameters to predict endometrial cancer

Abide

Ergen

Çöğendez

et al. 2018

Clinical Laboratory Analysis

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“…Although recent studies have clearly demonstrated that RDW is a reliable biomarker for cardiovascular morbidity and mortality, the underlying mechanism between inflammation and elevated RDW levels remains unclear. It is currently believed that cancer is developed from chronic inflammation . The mechanism of RDW elevation in patients with invasive hydatidiform mole is still under investigation, but the possible mechanisms include the following.…”

Section: Discussionmentioning

confidence: 99%

The potential value of red blood cell distribution width in patients with invasive hydatidiform mole

Zhang

Xie

Zhan

2019

Clinical Laboratory Analysis

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BackgroundRed blood cell distribution width (RDW) has attracted increasing attention in cancer. The aim of this study was to assess the changes of RDW in patients with invasive hydatidiform mole and analyze the relationship between RDW and invasive hydatidiform mole.MethodsA retrospective analysis was performed on 102 patients diagnosed as invasive hydatidiform mole in the First Affiliated Hospital of Guangxi Medical University from January 2009 to March 2018. A total of 120 healthy subjects were used as a control group. The Mann‐Whitney U test was used for comparison between the invasive hydatidiform mole and control groups. Comparison of RDW with other blood parameters was performed using Spearman's. The area under the ROC curve (AUC) and 95% confidence interval (95% CI) were also determined.ResultsThe RDW, platelet‐lymphocyte ratio (PLR), neutrophil‐lymphocyte ratio (NLR), and absolute lymphocyte count were significantly elevated in the invasive hydatidiform mole group compared with control group. The hemoglobin (Hb) concentration, mean red blood cell volume (MCV) and platelet count (PLT) were significantly lower in invasive hydatidiform mole group than control group. Grade III and above invasive hydatidiform mole patients had higher levels of RDW than grade I and II patients. Correlation analysis showed that RDW was negatively correlated with Hb, MCV, NLR, and neutrophil count, but positively correlated with PDW and different stages of invasive hydatidiform mole. The ROC curve showed that the AUC of the RDW was 0.660 (95% CI 0.581‐0.740; P < 0.01).ConclusionThis study reveals the potential value of RDW in invasive hydatidiform mole.

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“…There are many studies demonstrated that increased MPV was significantly related with colon cancer (Li et al, 2014), lung cancer (Kumagai et al, 2015), gastric cancer (Kılınçalp et al, 2014), endometrial carcinoma (Karateke et al, 2015) and in head and neck neoplasms (Eryilmaz et al, 2015). In the literature, increased N/L ratio was significantly related with the lung cancer (Kemal et al, 2014), gastric cancer (Kim et al, 2015), colon cancer (Absenger et al, 2013) and papillary thyroid cancer DOI:http://dx.doi.org/10.7314/APJCP.2016.17.4.2321 Inflammatory Hematological Parameters in Benign Nodular Goiter andPapillary Thyroid Cancer (Seretis et al, 2013).…”

Section: Discussionmentioning

confidence: 99%