RELATIONSHIP ADIPOCYTOKINES WITH ACTIVITY IMMUNE SYSTEM IN TYPE 2 DIABETES MELLITUS COMBINED WITH NONALCOHOLIC FATTY LIVER DISEASE (literature review and own data)

Abstract

In the review it was presented the literature data devoted to the study of the activity of the immune system, the levels of adipocytokines in patients with type 2 diabetes mellitus combined with non-alcoholic fatty liver disease. It was shown the results of own research anti- and pro-oxidant status and cytokine profile in patients with type 2 diabetes mellitus combined with non-alcoholic fatty liver disease. It was found an increase in pro-oxidant status indicators, levels of leptin and IL-6 combined with type 2 diabetes, obesity and NAFLD in comparison with patients with type 2 diabetes without NAFLD and obesity.