Relationship between ABO blood group phenotypes and hypertensive disorders of pregnancy: A hospital-based cross-sectional study in Kano, North-West Nigeria

Mukhtar, Isyaku Gwarzo; Yakubu, A.A; Yakasai, Bashir Wada; Ahmed, Salisu; Mansur, Shamsuddeen

doi:10.4103/nnjcr.nnjcr_28_19

Cited by 2 publications

(3 citation statements)

References 26 publications

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“…The frequency of ABO phenotypes in women with, is similar to that of pregnant women with normal blood pressure. Women in the AB blood group had the highest risk of developing GHD, and women in the O blood group had the lowest risk which is consistent with other studies [9,10].…”

Section: Discussionsupporting

confidence: 91%

Correlation between ABO blood group and gestational hypertensive disorder among pregnant women in Abuja, Nigeria

Ahamed Ibrahim Salihu,

Lateef Ariyo Adeniran,

Damilare Matthew Oladimeji

et al. 2023

Magna Sci. Adv. Res. Rev.

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Gestational hypertensive disorder (GHD) is among the major health problems in pregnant women. In this study, we assessed the relationship between gestational hypertensive disorder and ABO blood groups among women who attended the antenatal clinic at the University of Abuja Teaching Hospital, Abuja, Nigeria. Correlational study design was used on a total of 138 patients with sociodemographic characteristics and clinical data such as blood group, gestational hypertensive disorder status, maternal age at pregnancy, and parity were extracted. Descriptive statistics was carried out on the collected data and chi-square test for the test of association or Fisher’s exact where necessary. The maternal age of the women ranged from fifteen to fifty-one years old with a mean age of 30.7 ± 9.8. Clinical information revealed that 17 (12.3%) primigravida and 121 (87.7%) non-primigravida patients. The patients’ distribution by blood group revealed that 33 (23.9%), 32 (23.2%), 47 (34.1%) and 26 (18.8%) belonged to blood group A, B, AB, and O respectively. Our results showed a relationship between blood pressure and the ABO blood group but not significant with χ2 = 12.31 and p = 0.421 with blood pressure of 150/100–154/104 mmHg ranked highest in frequency among all the blood groups. Also, we observed a non- significant relationship between maternal age and the occurrence of GHD at χ2 =19.81 and p = 0.229 which implies that GHD is not associated with age but that blood pressure increases with gestational age. Interestingly, a significant relationship exists between gestational hypertension and parity at χ2 = 26.71 and p = 0.045. Blood group AB was more susceptible to gestational hypertensive disorder whereas blood groups O, A and B were less susceptible to it. We recommend increased awareness of GHD among pregnant women, all health workers, and the general public about its danger to pregnant mothers and fetuses.

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Section: Discussionsupporting

confidence: 91%

Correlation between ABO blood group and gestational hypertensive disorder among pregnant women in Abuja, Nigeria

Ahamed Ibrahim Salihu,

Lateef Ariyo Adeniran,

Damilare Matthew Oladimeji

et al. 2023

Magna Sci. Adv. Res. Rev.

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“…At present, the research conclusions about the influence of ABO blood group system on the occurrence and development of GHD are very contradictory. Many reports show that blood type has obvious or no obvious influence on the occurrence of GHD [11–18] . Therefore, the purpose of this study is to explore the effect of blood type on the risk of GHD by meta-analysis, and to provide a basis for clinical evaluation of GHD.…”

Section: Introductionmentioning

confidence: 99%

“…Many reports show that blood type has obvious or no obvious influence on the occurrence of Medicine ® OPEN GHD. [11][12][13][14][15][16][17][18] Therefore, the purpose of this study is to explore the effect of blood type on the risk of GHD by meta-analysis, and to provide a basis for clinical evaluation of GHD.…”

Section: Introductionmentioning

confidence: 99%

Relationship between ABO blood groups and gestational hypertensive disorders

Dilixiati

Sui²,

Ge³

et al. 2021

Medicine

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Background: The distribution of ABO blood group is related to the incidence of various diseases. Gestational hypertensive disorders (GHD) is one of the most important risk factors during pregnancy, which has certain heredity. It is reported that ABO blood type is associated with the risk of GHD. However, the results are still controversial. In this study, we conducted a systematic review and meta-analysis to clarify the relationship between ABO blood group and GHD. Methods: All eligible studies come from Embase, Cochrane Library, Pubmed, Chinese databases SinoMed, Chinese National Knowledge Infrastructure, Chinese Scientific Journals Database, and Wanfang Data. The retrieval time is from the establishment of the database to March 2021. The language will be limited to Chinese and English. The 2 reviewers will be responsible for the selection of the study, the extraction of data, and the evaluation of the quality of the research. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the corresponding associations. Sensitivity analysis, publication bias assessment, and heterogeneity test were performed using STATA 16.0. Results: The results of this meta-analysis will be published in peer-reviewed journals. Conclusion: This study will provide evidence to support the relationship between ABO blood group and the risk of GHD. Ethics and dissemination: The private information from individuals will not be published. This systematic review also will not impair endangering participants’ rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. OSF Registration number: DOI 10.17605/OSF.IO/3X9YZ.

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Relationship between ABO blood group phenotypes and hypertensive disorders of pregnancy: A hospital-based cross-sectional study in Kano, North-West Nigeria

Cited by 2 publications

References 26 publications

Correlation between ABO blood group and gestational hypertensive disorder among pregnant women in Abuja, Nigeria

Correlation between ABO blood group and gestational hypertensive disorder among pregnant women in Abuja, Nigeria

Relationship between ABO blood groups and gestational hypertensive disorders

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