Relationship between ABO Blood Groups and Helicobacter Pylori Infection among Patients with Dyspepsia

Baqir, Gaidaa Kadhum; Al-Sulami, Amin; Hamadi, Saad Shaheen

doi:10.5171/2016.688370

Cited by 6 publications

(4 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, we found that the relationship between the Rapid urease test and PCR appears with 94.6% sensitivity and 97.3% specificity, making it a highly sensitive test in comparison to PCR. This is comparable to another study that discovered that the rates of H. pylori detection by RUT, RDT, culture, and PCR were, respectively, 66.5%, 69.5%, 71%, and 67.5% with no discernible difference [20] Primary isolation of H. pylori from a biopsy specimen is a difficult process. The normal success rates for primary isolation of H. pylori from biopsy samples are reported to be in the range of 70% to 80% with 90% to 95% sensitivity and 100% specificity [21].…”

Section: Rapid Urease Test Results and Its Relation To Pcr Resultssupporting

confidence: 80%

Molecular Detection of Antimicrobial Resistant Genes to Clarithromycin in Helicobacter pylori at Basrah, Iraq

2023

JPTCP

View full text Add to dashboard Cite

The primary cause of gastritis and peptic ulcers, as well as gastric cancer and gastric mucosaassociated lymphoid tissue lymphoma, is the bacterium Helicobacter pylori. When an infection with H. pylori is discovered, eradication therapy should be started, and it is best if it is successful the first time. According to international standards, in some instances, medication susceptibility testing should be used to tailor treatment. The most widely used first-line treatment is still triple therapy, which combines a proton-pump inhibitor (PPI) with amoxicillin and clarithromycin (PPI-AC). This casecontrol study included 112 patients (55 males and 57 females), aged between 15 and 74, with a variety of gastritis symptoms, and 112 randomly chosen controls (59 males and 53 females), aged between 15 and 74, who were H. pylori negative. RUT and PCR were used for diagnosis of the bacteria. Realtime PCR was used to genotype two SNPs of the gene 23S rRNA, A2142G, and A2143G, which confer clarithromycin resistance. The rate of resistance to clarithromycin were 65.2% which consider high according to similar studies and this resistant appear that it was not associated with any of age, diabetes and smoking and it was result from point mutation in 23sRNA gene.

show abstract

Section: Rapid Urease Test Results and Its Relation To Pcr Resultssupporting

confidence: 80%

Molecular Detection of Antimicrobial Resistant Genes to Clarithromycin in Helicobacter pylori at Basrah, Iraq

2023

JPTCP

View full text Add to dashboard Cite

show abstract

“…In well documented studies, O blood group has been found to have a frequency of about 45%, Agroup about 41%, whereas B is 10% and AB only 4%. [33].…”

Section: Discussionmentioning

confidence: 99%

Helicobacter pylori infection Evluated by C14-urea Breath test and it`s Relation with age, sex and ABO/Rhesus blood Groups in Patients with Gastrointestinal complaints in Kirkuk City / Iraq.

Salih¹

2019

Tikrit J. Pure Sci.

View full text Add to dashboard Cite

There was significant difference between genders and H. pylori infection (P<0.05). From the 176 patients attending private laboratories in Kirkuk city for the period from 1/8/2016 to 1/4/2017, 86(48.86%) belonged to blood group O, 42(23.86%) to A, 41(23.29%) to B and 7 (3.97%) to AB and There was statistically significant difference (P<0.05) in the incidence of H. pylori infection between these groups, there was significant correlation between the presence of particular blood group in H. pylori positive patients related to the reported frequency of the blood groups in Kirkuk population, the correlation between the Rh factor and positive H. pylori patients was not significant to the frequency of the Rh factor in the population (88.06% Rh+ and 11.93% Rh-). the H. pylori positive test was slightly, but not significantly lower in comparison with the negitive H. pylori patients test values showed a highly significant difference (P<0.01) in H. pylori posative and H. pylori negitive patients., in adults H. pylori infection depend upon gender, blood groups but they do not depend upon the Patients age or Rh factore.

show abstract

“…The acid in the stomach and the digestive enzyme 'pepsin' combine and result in a synergistic effect leading to ulcer formation. 4 It is mostly prevalent in areas with lower socio-economic status and poor hygienic conditions. 5 H. pylori has a very high ability to live in a very harsh gastric environment accompanied by acidity, peristalses, and attacks by phagocytes.…”

Section: Introductionmentioning

confidence: 99%

Incidence Of Helicobacter Pylori Infection in Association With ABO Blood Groups

Zehra,

Sabir,

Sarwar

et al. 2024

JRMC

View full text Add to dashboard Cite

Objective: The study aimed to investigate the association between ABO blood groups and helicobacter infection. Method: 150 participants, including 93 females and 57 males between the age group of 18-60 years, were involved in the study. A sample of 3 ml blood was collected and screened against H. pylori antibodies (IgG) by H. pylori rapid diagnostic kit. ABO and Lewis antigen phenotypes were determined with a macroscopic agglutination technique. Results: According to the study's findings, there were 55.42% women (46/83) and 44.5% men (37/83) among the 83 seropositive patients, while 70.14% women (47/67) and 29.85% men (20/67) were found among the 67 seronegative patients. The findings of this study reveal that those with the blood groups O+ and B+ have an estimated 25.3% (21/83) higher risk of H. pylori infection, whereas when seronegative individuals were investigated, it was discovered that blood groups 0+ were also leading, 28.4% (19/67), indicating that there was no significant difference between H. pylori seropositive and seronegative patients (p-value = 0.5146). Other factors, such as gender and family history, did not significantly affect the incidence of H. pylori. Conclusion: It was concluded from the study that no significant difference was observed between trends of H. pylori seropositive patients and seronegative individuals having different blood groups. Keywords: ABO Blood Group, Peptic Ulcer, Seronegative Pyloric patients, Seropositive Pyloric patients.

show abstract

Relationship between ABO Blood Groups and Helicobacter Pylori Infection among Patients with Dyspepsia

Cited by 6 publications

References 21 publications

Molecular Detection of Antimicrobial Resistant Genes to Clarithromycin in Helicobacter pylori at Basrah, Iraq

Molecular Detection of Antimicrobial Resistant Genes to Clarithromycin in Helicobacter pylori at Basrah, Iraq

Helicobacter pylori infection Evluated by C14-urea Breath test and it`s Relation with age, sex and ABO/Rhesus blood Groups in Patients with Gastrointestinal complaints in Kirkuk City / Iraq.

Incidence Of Helicobacter Pylori Infection in Association With ABO Blood Groups

Contact Info

Product

Resources

About