Relationship between adherence to Dietary Approaches to Stop Hypertension (DASH) diet indices and incidence of depression during up to 8 years of follow-up

Abstract

Objective: Our aim was to evaluate the relationship between adherence to different Dietary Approaches to Stop Hypertension (DASH) diet indices and the risk of depression. Design: In a prospective study we assessed 14 051 participants of a dynamic (permanently ongoing recruitment) prospective cohort (the Seguimiento Universidad de Navarra (SUN) Project), initially free of depression. At baseline, a validated FFQ was used to assess adherence to four previously proposed DASH indices (Dixon, Mellen, Fung and Günther). To define the outcome we applied two definitions of depression: a less conservative definition including only self-reported physician-diagnosed depression (410 incident cases) and a more conservative definition that required both clinical diagnosis of depression and use of antidepressants (113 incident cases). Cox regression and restricted cubic splines analyses were performed. Results: After a median follow-up period of 8 years, the multiple-adjusted model showed an inverse association with the Fung DASH score (hazard ratio (HR) = 0·76; 95 % CI 0·61, 0·94) when we used the less conservative definition of depression, and also under the more conservative definition (HR = 0·63; 95 % CI 0·41, 0·95). We observed a weak inverse association with the Mellen DASH score, but no statistically significant association was found for the other definitions. The restricted cubic splines analyses suggested that these associations were nonlinear (U-shaped). Conclusions: Moderate adherence to the DASH diet as operationalized by Fung and Mellen was related to lower depression risk. Since these associations were non-linear, additional prospective studies are required before the results can be generalized and clinical recommendations can be given.

Dietary Habits and Risk of Kidney Function Decline in an Urban Population

“…Others have operationalized DASH diet accordance differently, and some clinical outcomes have been found to be differentially associated with these various indices. 40,41 Third, data on some important factors related to dietary intake and potentially to CKD, such as food additives 42 , nutritional supplements 43 , availability of healthful foods in neighborhood stores and physical activity 44 were unavailable. Fourth, some level of error has been associated with the measurement of food consumption.…”

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“…Adoption of recommended dietary patterns such as the DASH, Mediterranean, or USDA MyPlate Diets might help manage these disorders, as well improve overall health. lower risk of developing depression over the 8.5 years of a follow-up study by PerezCornago et al (128). In addition, a balanced Japanese dietary pattern (high intakes of vegetables, fruits, mushrooms, and soy products) and adequate serum folate intake were associated with less depression (129).…”

The Mediterranean diet and depression – can a healthier dietary pattern reduce the risk of depression?

“…However, this dietary pattern is not as well researched and only a single cohort study was available (Perez‐Cornago et al . ), which compared four variants of the DASH diet. Only one DASH diet score, proposed by Fung et al .…”

“…No significant risk reduction for depressive outcomes was found for any estimates calculated for the DASH diet. However, this dietary pattern is not as well researched and only a single cohort study was available (Perez-Cornago et al 2017), which compared four variants of the DASH diet. Only one DASH diet score, proposed by Fung et al (2008), was found to be related to reduced risk of depression (HR = 0.63; 95% CI: 0.41, 0.95).…”