Relationship between allergic diseases and mental disorders in women: A systematic review and meta-analysis

Abstract

BackgroundThe relationship between allergic diseases (AD) and mental disorders (MD) in women has not been fully systematically evaluated. We aimed at validating this correlation.MethodsThe relevant cohort and case-control studies from the establishment of the database to February 18, 2022 in PubMed, Embase, and Cochrane library were searched by computer. The researchers conducted the quality evaluation of the included articles by reviewing and discussing with reference to relevant standards, and conducted the analysis of the correlation between female patients with AD and MD by using Review Manager 5.4.ResultsSix observational studies from 2631 studies (n = 1160858 women) were assessed as medium and high-quality studies. The meta-analysis demonstrated that AD was correlated with MD in female patients (OR = 1.21, 95%CI: 1.14–1.29), including asthma (OR = 1.16, 95%CI: 1.11–1.22), allergic rhinitis (OR = 1.31, 95%CI: 1.06–1.63), and atopic dermatitis in women (OR = 1.37, 95%CI: 1.24–1.50) were associated with MD. At the same time, subgroup analysis was performed according to region, study design, criteria of AD and MD, and the results demonstrated that both AD and MD were correlated in these different conditions.ConclusionAllergic diseases in female patients do have an association with mental disorders.Systematic review registration[https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD42022311146].

Association between allergic diseases, generalized anxiety disorder, and depressive symptoms in South Korean adolescents: a secondary data analysis of the 2022 Korea Youth Risk Behavior Survey

“…Studies on adolescents with allergic disease focused on its impact on suicidal ideation [16], relationship between sleep disorder and emotional characteristics [16,17], and assessment of emotional state and behavioral problems in specific allergic diseases [8,10]. Although allergic diseases' underlying cause remains the same, their timing of occurrence and symptoms vary across individuals [1,18]. Therefore, different approaches for specific allergic diseases are needed.…”

“…Therefore, different approaches for specific allergic diseases are needed. Liu et al's [18] study on allergies in women highlighted the necessity of analyzing specific disease-based allergies. However, in South Korea, limited research has conducted such disease-specific analyses.…”