Relationship between antisocial behaviour, attention-deficit hyperactivity disorder and maternal prenatal smoking

Button, Tanya M. M.; Thapar, Anita; McGuffin, Peter

doi:10.1192/bjp.187.2.155

Cited by 103 publications

(86 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…and "How many cigarettes/day did you smoke whilst pregnant?" These questions are similar to those found in most other assessment instruments (e.g., the Centers for Disease Control and Prevention Pregnancy Risk Assessment Monitoring System Questionnaire; see Beck et al, 2002) and like those found in most other studies (particularly those assessing large samples, e.g., Button et al, 2005;Fergusson et al, 1998;Maughan et al, 2004;Wakschlag & Hans, 2002). Because amount of cigarettes reportedly smoked tends to be a "rounded" number, for example, 5, 10, 15, and so forth, mothers were classified into one of three groups (0, 1-9, ≥10 cigarettes/ day).…”

Section: Maternal Prenatal Smokingsupporting

confidence: 77%

Maternal prenatal smoking, parental antisocial behavior, and early childhood physical aggression

et al. 2008

View full text Add to dashboard Cite

This study investigated joint effects of maternal prenatal smoking and parental history of antisocial behavior on physical aggression between ages 17 and 42 months in a population sample of children born in Québec (N = 1,745). An analysis of variance (ANOVA) showed significant main effects of maternal prenatal smoking and a significant interaction between maternal prenatal smoking and mother's history of antisocial behavior in the prediction of children's probability to display high and rising physical aggression. The interaction indicated that the effects of heavy smoking during pregnancy (≥10 cigarettes/day) were greater when the mother also had a serious history of antisocial behavior. The effects remained significant after the introduction of control variables (e.g., hostile-reactive parenting, family functioning, parental separation/divorce, family income, and maternal education). Another significant interaction not accounted for by control variables was observed for maternal prenatal smoking and family income, indicating more serious effects of maternal prenatal smoking under relatively low-income, conditions. Both interactions indicate critical adversities that, in combination with maternal prenatal smoking, have supraadditive effects on (the development of) physical aggression during early childhood. These findings may have implications for the selection of intervention targets and strategies.Physical aggression is present in the majority of young children and it decreases with age as emotion regulation skills and alternative conflict-resolution strategies emerge, aided by development of language and cognitive abilities (Tremblay, 2000;Tremblay & Nagin, 2005). However, it is also clear that those children who show the highest levels of physical aggression during early childhood are most at risk of chronic physical aggression throughout childhood (Côté, Vaillancourt, LeBlanc, Nagin, & Tremblay, 2006; NICHD Early Child Care Research Network, 2004), followed by serious violent and nonviolent delinquency during adolescence (Broidy et al., 2003;Nagin & Tremblay, 1999). Recent studies show that children with early, persistent aggression show not only more externalizing problems at CIHR Author Manuscript CIHR Author Manuscript CIHR Author Manuscriptfollow-up but also more internalizing and peer problems (e.g., depression, loneliness, poor friendship quality) compared with children on the lower and desisting aggression trajectories (Campbell, Spieker, Burchinal, Poe, & The NICHD Early Child Care Research Network, 2006). It is therefore important to determine which factors or combinations of factors predict consistently high physical aggression during early childhood.Research has linked maternal prenatal smoking to early childhood physical aggression (Huijbregts, Séguin, Zoccolillo, Boivin, & Tremblay, 2007;Tremblay et al., 2004) and to other externalizing (Orlebeke, Knol, & Verhulst, 1997) and disruptive behavior problems (Wakschlag, Leventhal, Pine, Pickett, & Carter, 2006). Maternal prenatal smoking...

show abstract

Section: Maternal Prenatal Smokingsupporting

confidence: 77%

Maternal prenatal smoking, parental antisocial behavior, and early childhood physical aggression

et al. 2008

View full text Add to dashboard Cite

show abstract

“…Genetic risk for antisocial behavior may contribute to a mother's likelihood of SDP and may confer vulnerability to externalizing problems when inherited by offspring. Standard correlational (Button, Thapar, & McGuffin, 2005;Knopik et al, 2005;Maughan, Taylor, Caspi, & Moffitt, 2004;Thapar et al, 2003) have used an approach, including a measure of SDP in a standard twin study, that assumes the relation is purely environmental (Purcell & Koenen, 2005;Turkheimer, D'Onofrio, Maes, & Eaves, 2005). Therefore, previous studies have been unable to explore the possibility that passive rGE accounts for observed relations between SDP and externalizing.…”

Section: Nih-pa Author Manuscriptmentioning

confidence: 99%

“…Standard correlational research approaches, in which environmental and genetic risks are confounded, are ineffective in delineating whether associations between externalizing problems and SDP are due to environmental causation or passive rGE (D'Onofrio et al, 2003;Moffitt, 2005;Rutter, Pickles, Murray, & Eaves, 2001). Moreover, most of the genetically informed studies of SDP and externalizing problems in offspring (Button, Thapar, & McGuffin, 2005;Knopik et al, 2005;Maughan, Taylor, Caspi, & Moffitt, 2004;Thapar et al, 2003) have used an approach, including a measure of SDP in a standard twin study, that assumes the relation is purely environmental (Purcell & Koenen, 2005;Turkheimer, D'Onofrio, Maes, & Eaves, 2005). Therefore, previous studies have been unable to explore the possibility that passive rGE accounts for observed relations between SDP and externalizing.…”

mentioning

confidence: 99%

Smoking during pregnancy and offspring externalizing problems: An exploration of genetic and environmental confounds

et al. 2008

View full text Add to dashboard Cite

Previous studies have documented that smoking during pregnancy (SDP) is associated with offspring externalizing problems, even when measured covariates were used to control for possible confounds. However, the association may be due to non-measured environmental and genetic factors that increase risk for offspring externalizing problems. The current project used the National Longitudinal Survey of Youth and their children, ages 4-10 years, to explore the relations between SDP and offspring conduct problems (CP), oppositional-defiant problems (ODP), and attention deficit hyperactivity problems (ADHP) using methodological and statistical controls for confounds. When offspring were compared to their own siblings who differed in their exposure to prenatal nicotine, there was no effect of SDP on offspring CP and ODP. This suggests that SDP does not have a causal effect on offspring CP and ODP. There was a small association between SDP and ADHP, consistent with a causal effect of SDP, but the magnitude of the association was greatly reduced by methodological and statistical controls. Genetically informed analyses suggest that unmeasured environmental variables influencing both SDP and offspring externalizing behaviors account for the previously observed associations. That is, the current analyses imply that important unidentified environmental factors account for the association between SDP and offspring externalizing problems, not teratogenic effects of SDP. Keywordssmoking during pregnancy; conduct problems; externalizing problems; ADHD; children of twins; causation Smoking during pregnancy (SDP) has been consistently linked with externalizing problems in offspring, particularly in males (reviews in Cnattingius, 2004;Huizink & Mulder, 2005;Wakschlag & Hans, 2002;Wakschlag, Pickett, Cook, Benowitz, & Leventhal, 2002). SDP has been associated with parent-reported conduct problems (Ernst, 2001), arrest history from national crime registries (Brennan, Grekin, & Mednick, 1999;Rasanen et al., 1999), contact 2 All correspondence should be sent to: Brian D'Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, 1101 E. 10th St., Bloomington, IN 47405, bmdonofr@indiana.edu. NIH Public Access Author ManuscriptDev Psychopathol. Author manuscript; available in PMC 2013 August 08. NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscriptwith police obtained by city police records (Gibson, Piquero, & Tibbets, 2000), Oppositional Defiant Disorder (Wakschlag & Keenan, 2001), Conduct Disorder (Fergusson, Woodward, & Horwood, 1998;Wakschlag & Hans, 2002;Wakschlag & Keenan, 2001;Wakschlag et al., 1997;Weissman, Warner, Wickramaratne, & Kandel, 1999) and Attention-Deficit/ Hyperactivity Disorder (Mick, Biederman, Faraone, Sayer, & Kleinman, 2002;Rodriguez & Bohlin, 2005).Reviews of the literature note that the association is consistent with a causal connection because the association is specific to externalizing problems, has been found across diverse samples and measures, demonstr...

show abstract

“…The strength of association does differ slightly between studies, although generally it appears that the children of smokers are approximately 1.5-3 times more likely to have ADHD or ADHD symptoms than the children of non-smokers. Some studies which analyzed ADHD symptoms based on Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria or DuPaul Rating Scale indicate the statistically significant association with the exposure to tobacco smoke [58,[60][61][62][63][64]. In opposite, the results from Hill et al [65], Nigg et al [66], Thapar et al [67] and Lavigne et al [68] were not statistically significant.…”

Section: Ijomeh 2012;25(4) 336mentioning

confidence: 99%

Exposure to environmental and lifestyle factors and attention-deficit / hyperactivity disorder in children — A review of epidemiological studies

Polańska¹,

Jurewicz²,

Hanke³

2012

International Journal of Occupational Medicine and Environmental Health

View full text Add to dashboard Cite

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Although the mechanisms that lead to the development of ADHD remain unclear, genetic and environmental factors have been implicated. These include heavy metals and chemical exposures, nutritional and lifestyle/psychosocial factors. The aim of this review was to investigate the association between ADHD or ADHD-related symptoms and widespread environmental factors such as phthalates, bisphenol A (BPA), tobacco smoke, polycyclic aromatic hydrocarbons (PAHs), polyfluoroalkyl chemicals (PFCs) and alcohol. Medline, PubMed and Ebsco search was performed to identify the studies which analyze the association of prenatal and postnatal child exposure to environmental toxicants and lifestyle factors and ADHD or ADHD-related symptoms. The review is restricted to human studies published since 2000 in English in peer reviewed journals. Despite much research has been done on the association between environmental risk factors and ADHD or ADHD symptoms, results are not consistent. Most studies in this field, focused on exposure to tobacco smoke, found an association between that exposure and ADHD and ADHD symptoms. On the other hand, the impact of phthalates, BPA, PFCs, PAHs and alcohol is less frequently investigated and does not allow a firm conclusion regarding the association with the outcomes of interest.

show abstract

Relationship between antisocial behaviour, attention-deficit hyperactivity disorder and maternal prenatal smoking

Abstract: Both antisocial behaviour and ADHD symptoms in offspring are independently influenced by maternal prenatal smoking during pregnancy.

Cited by 103 publications

References 21 publications

Maternal prenatal smoking, parental antisocial behavior, and early childhood physical aggression

Maternal prenatal smoking, parental antisocial behavior, and early childhood physical aggression

Smoking during pregnancy and offspring externalizing problems: An exploration of genetic and environmental confounds

Exposure to environmental and lifestyle factors and attention-deficit / hyperactivity disorder in children — A review of epidemiological studies

Contact Info

Product

Resources

About