Relationship Between Bariatric Surgery and Gastroesophageal Reflux Disease: a Systematic Review and Meta-analysis

Do we understand the pathophysiology of GERD after sleeve gastrectomy?

“…[10][11][12][13][14][15][16] According to a metaanalysis of randomized clinical trials comparing the outcomes of SG versus RYGB, the odds ratio (OR) for GERD after SG is four times higher (OR = 4.08, P < 0.001). 9 Furthermore, SG is a significant risk factor for the development of de novo reflux, the occurrence of which correlates with the length of follow-up, varying between 8% and 30 percent. 17,18 GERD is the major cause of impaired quality of life after bariatric surgery and may be associated with a decrease in physical functioning as well as an increase in mental and emotional problems, resulting in poorer social functioning.…”

“…While up to 30% of patients may experience some GERD symptoms after SG, most do not require operative therapy and can be treated successfully with medication. 9 According to two large randomized controlled trials (RCTs) with 5-year follow-up periods, the conversion rate of SG to RYGB due to severe GERD was 6-8 percent. 10,14 In order to successfully treat post-sleeve gastrectomy GERD, the cause of the problem must first be identified using a stepwise diagnostic approach (Fig.…”

“…[6][7][8] However, depending on the type of bariatric procedure, GERD can worsen following surgery and, in some cases, even new onset GERD can occur. 9 As a consequence, GERD remains a relevant problem for many bariatric patients, and especially for those who have undergone sleeve gastrectomy (SG), although de novo GERD also occurs in about 10% of patients following Roux-Y gastric bypass (RYGB). 10 In our narrative review, doi: 10.1111/nyas.14467 possible pathomechanisms of GERD after SG are discussed, and available strategies for preventing and treating GERD after SG are elucidated.…”

A retrospective study on the evaluation of the symptoms, medications and improvement of the quality of life of patients undergoing robotic surgery for gastroesophageal reflux disease

“…There are some lifestyle changes that can reduce the intensity of symptoms, including smoking cessation, reduction of alcohol consumption, weight loss and particularly A retrospective study on the evaluation of the symptoms, medications and improvement of the quality of life of patients undergoing robotic surgery for gastroesophageal reflux disease SOFIA K. KONSTANTINIDOU 1 , PENELOPE KOSTARAS 2 , GEORGIOS-ELEFTHERIOS ANAGNOSTOPOULOS 2 , SOPHIA-LIBERTY MARKANTONIS 2 , VANGELIS KARALIS 2 and KONSTANTINOS KONSTANTINIDIS 3 the reduction of abdominal obesity, avoidance of fatty foods and coffee consumption, and avoidance of eating late-night meals (5,(8)(9)(10)(11)(12)(13)(14)(15)(16). Posture during night sleep also appears to have a significant role in the improvement of symptoms; a bed head higher than 15-20 cm appears the least effective (1).…”

Endoscopic gastric plication for the treatment of GERD and underlying class I obesity

“…9 Furthermore, sleeve gastrectomy, which is the most common bariatric surgery, is a refluxinducing procedure, and gastric bypass is rarely performed in patients with class I obesity. [10][11][12] Therefore, management of refractory GERD in this population remains challenging.…”