Relationship between Body Composition and Biochemical Parameters with Antioxidant Status in a Healthy Cohort of Postmenopausal Women

Vázquez-Lorente, Héctor; Herrera-Quintana, Lourdes; Molina-López, Jorge; Gamarra-Morales, Yénifer; López-González, Beatriz; Planells, Elena

doi:10.3390/metabo12080746

Cited by 2 publications

(1 citation statement)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…What is more, obtained clinical results in the healthy aged population showed discrepancies. Kozakiewicz and colleagues described a decrease in crucial activity of antioxidative enzymes with the simultaneous intensity of lipids peroxidation [52], while Vázquez-Lorente et al argued that in a postmenopausal population, antioxidant parameter values showed no changes with aging [53], but the activity of total antioxidant capacity were affected by body composition and directly related to plasma proteins [54]. Differences in the results of the researchers may be explained by the selection of different populations, age ranges or genders, co-morbidities or even no disease existence in investigated age groups.…”

Section: Theories Of Aging Oxidative Stress and Inflammagingmentioning

confidence: 99%

Inflammation and Oxidative Stress in Frailty and Metabolic Syndromes—Two Sides of the Same Coin

Dzięgielewska-Gęsiak

Muc-Wierzgoń

2023

Metabolites

View full text Add to dashboard Cite

In developed countries, aging is often seen as typical, but it is made complicated by many disorders and co-morbidities. Insulin resistance seems to be an underlying pathomechanism in frailty and metabolic syndromes. The decline in insulin sensitivity leads to changes in the oxidant–antioxidant balance and an accelerated inflammatory response, especially by adipocytes and macrophages in adipose tissue, as well as muscle mass density. Thus, in the pathophysiology of syndemic disorders—the metabolic syndrome and frailty syndrome—an extremely important role may be played by increased oxidative stress and pro-inflammatory state. Papers included in this review explored available full texts and the reference lists of relevant studies from the last 20 years, before the end of 2022; we also investigated the PubMed and Google Scholar electronic databases. The online resources describing an elderly population (≥65 years old) published as full texts were searched for the following terms: “oxidative stress and/or inflammation”, “frailty and/or metabolic syndrome”. Then, all resources were analyzed and narratively described in the context of oxidative stress and/or inflammation markers which underlie pathomechanisms of frailty and/or metabolic syndromes in elderly patients. So far, different metabolic pathways discussed in this review show that a similar pathogenesis underlies the development of the metabolic as well as frailty syndromes in the context of increased oxidative stress and acceleration of inflammation. Thus, we argue that the syndemia of the syndromes represents two sides of the same coin.

show abstract

Section: Theories Of Aging Oxidative Stress and Inflammagingmentioning

confidence: 99%

Inflammation and Oxidative Stress in Frailty and Metabolic Syndromes—Two Sides of the Same Coin

Dzięgielewska-Gęsiak

Muc-Wierzgoń

2023

Metabolites

View full text Add to dashboard Cite

show abstract

Plasma Antioxidant Capacity Is Related to Dietary Intake, Body Composition, and Stage of Reproductive Aging in Women

Tijerina,

Fonseca,

Aguilera-González

et al. 2024

Antioxidants

View full text Add to dashboard Cite

Background: women aging is a normal process of life; however, hormonal changes create an imbalance between prooxidants and antioxidants and could be measured as the antioxidant capability (AC) of an organism. Objective: to find the association between plasma AC levels, dietary intakes, and body composition in 18–64-year-old women living in the northeast of Mexico. Methods: A total of n = 514 women (18–64 years old) were grouped according to STRAW criteria as reproductive, menopausal transition, and postmenopausal. Anthropometrics, body mass index (BMI), weight–hip ratio (WHR), and weight–height ratio WHtR were determined, and percentage of body fat was analyzed by bioelectrical impedance. Dietary intake of macronutrients and vitamins A, E, and C were analyzed by a 3-day food recall. The AC status in plasma was analyzed by the ORACFL assay. Results: Plasma AC levels were higher in postmenopausal women (815 µmol TE/L), and menopausal transition women (806 µmol TE/L) than in reproductive women (633 µmol TE/L). BMI was overweight (>25 kg/m2) in all three groups. WHtR and WHR are above the healthy limit of 0.5 and 0.8, respectively for both menopausal transition and postmenopausal women. In reproductive women, negative relationships were calculated between plasma AC and age (Rho = −0.250, p = 0.007), BMI (Rho = −0.473, p < 0.001), WHtR (Rho = −0.563, p < 0.001), WHR (Rho = −0.499, p < 0.001), and % body fat (Rho = −0.396, p < 0.001). A negative association was determined between plasma AC and WHtR in reproductive women (B = −2.718, p = 0.026). No association resulted for those in menopausal transition, and a positive association was obtained between plasma AC and protein (B = 0.001, p = 0.024) and vitamin E (B = 0.003, p = 0.013) intakes in postmenopausal women. Conclusions: the antioxidant capability (AC) in plasma was lower in reproductive women, and anthropometric parameters marking decreased physical fitness were associated with decreased AC.

show abstract

Relationship between Body Composition and Biochemical Parameters with Antioxidant Status in a Healthy Cohort of Postmenopausal Women

Cited by 2 publications

References 49 publications

Inflammation and Oxidative Stress in Frailty and Metabolic Syndromes—Two Sides of the Same Coin

Inflammation and Oxidative Stress in Frailty and Metabolic Syndromes—Two Sides of the Same Coin

Plasma Antioxidant Capacity Is Related to Dietary Intake, Body Composition, and Stage of Reproductive Aging in Women

Contact Info

Product

Resources

About