Relationship between body temperature, weight, and hematological parameters of black tufted‐ear marmosets (<i>Callithrix penicillata</i>)

Pereira, Leonardo Costa; Barros, Marília

doi:10.1111/jmp.12214

Cited by 6 publications

(5 citation statements)

References 32 publications

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“…We were thus unable to ascertain the subjects’ exact history with restraint procedures, yet they have been restrained >50 times in a manner similar to that used in present study. Furthermore, all subjects were implanted with a subcutaneous radio-frequency transponding identification microchip (BioThermo 985 LifeChip, Destron Fearing, South St. Paul, MN, United States) that provides a reliable subcutaneous temperature (SCT) measure within a range of 0 to 50°C (for more details see Pereira and Barros, 2016).…”

Section: Methodsmentioning

confidence: 99%

“…The marmosets’ right and left TMT were assessed with an infrared digital ear thermometer (IFR 100 Dual Mode Thermometer, Microlife, Brazil). It has an operating temperature range of 10 to 50°C, a sensitivity of 0.1°C and an accuracy of ±0.2°C (between 32.0 and 42.2°C), and can reliably assess the TMT of small neotropical primates (Pereira and Barros, 2016; Pereira et al, 2018). Six TMT readings were made, at 5 s intervals: three in the left ear and three in the right ear.…”

Section: Methodsmentioning

confidence: 99%

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Rightward Tympanic Membrane Temperature Bias During Acute Restraint-Isolation Stress in Marmoset Monkeys

2019

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Restraint is widely used to experimentally assess stress-induced effects. Surprisingly, little is known on how marmosets – an increasingly used small primate – process and respond to restraint stress. Here, we assessed blood cortisol concentration and tympanic membrane temperatures (TMT) in adult marmoset monkeys ( Callithrix penicillata ) during 0, 15, or 30 min of restraint and social isolation in a small cage. TMT reflects blood flow to the cerebral hemispheres, which in turn reflects neural activity. Baseline TMT were subtracted from post-test measures to establish shifts in blood flow possibly induced by ipsilateral brain activity. Cortisol was assayed immediately after the post-test assessment of the TMT. Marmosets restrained-isolated for 15 or 30 min had higher cortisol levels than the non-restrained-isolated group. Furthermore, significant changes in TMT were detected only in the right ear of the restrained-isolated groups, this effect being unrelated to overall body temperature or the time needed to capture/measure the TMT. Adult marmosets thus readily perceive a significant reduction in their range of movement as an event of sufficient negative intensity and/or duration to activate a pertinent neuroendocrine response. Also, an asymmetrical shift in their TMT reflects that such an aversive event may be rightwardly biased in this primate.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Rightward Tympanic Membrane Temperature Bias During Acute Restraint-Isolation Stress in Marmoset Monkeys

2019

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“…Another point of discussion is the fact that the initial presentation with hemorrhagic gastroenteritis, prostration, and anemia, not associated with the presence of gastrointestinal parasites, documentable intestinal mass or foreign body, pancreatitis, or other conditions in the complementary exams performed, motivated the use of systemic antibiotics. The rectal temperature near the upper limit was also considered a clue due to the relationship between body temperature and hematological parameters in this species (Pereira & Barros 2016) and the unfeasibility of performing a complete blood count due to volume sample limitation. The gut microbiome has a strong relationship with insulin resistance and diabetes in people.…”

Section: Discussionmentioning

confidence: 99%

Oral metformin for type-2 diabetes mellitus treatment in a black-tufted marmoset (Callithrix penicillata)

Duz,

Surita,

Machado

et al. 2024

Pesq. Vet. Bras.

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Type-2 diabetes mellitus (T2DM) is characterized by defects in insulin secretion and combined peripheral resistance to the hormone. Several non-human primates (NHP) species develop T2DM, mainly captive animals with reduced physical activity and incorrect feeding. This case report describes the T2DM treatment of a black-eared marmoset (Callithrix penicillata) by diet reformulation and metformin oral administration. An adult female was diagnosed with T2DM after hyperglycemia and high serum fructosamine associated with glycosuria and obesity. Metformin hydrochloride (125mg/animal, orally, q24h) associated with feeding intervention was started. After 26 days, a significant reduction in weight, glycemia, and serum fructosamine could be observed, showing satisfactory results for the adopted therapy. Metformin is considered a safe drug for T2DM treatment due to its low hypoglycemia risk. The new diet consisted of sweet potato, squash, and varied fruits offered twice daily. In addition, thawed-mice newborns, egg whites, and small portions of pelleted primate food. In the present report, metformin use, associated with a low glycemic index diet, was effective in treating this particular marmoset and may present a potential for T2DM treatment in other NHPs.

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“…All subjects were implanted with a subcutaneous radiofrequency transponder identification microchip that had a temperature-recording sensor (BioThermo 985 LifeChip, Destron Fearing, South St. Paul, MN, USA). For more details see Pereira and Barros ( 2016 ).…”

Section: Methodsmentioning

confidence: 99%

“…The right and left TMT were assessed with an infrared digital ear thermometer used previously in marmosets (IFR 100 Dual-Mode Thermometer, Microlife, Brazil; Pereira and Barros, 2016;Pereira et al, 2018Pereira et al, , 2019. It had an operating temperature range of 10-50 o C, sensitivity of 0.1 o C, and accuracy of ± 0.2 o C (between 32.0 and 42.2 o C).…”

Section: Tmt and Sct Assessment And Analysesmentioning

confidence: 99%

Time-Dependent Changes in Cortisol and Tympanic Temperature Lateralization During Food Deprivation Stress in Marmoset Monkeys

Pereira

Maior

Barros

2020

Front. Behav. Neurosci.

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Temporal information about food availability can be easily entrained, as in the case of fixed feeding routines of captive animals. A sudden unintentional or deliberate delay (e.g., food deprivation—FD) leads to frustration and psychological stress due to the loss of temporal predictability. How marmosets—an increasingly used small primate—process and respond to FD stress has not been previously assessed. Here we delayed the routine feeding of adult captive marmosets for 3 or 6 h. Blood cortisol concentration was used as a hormonal measure of the stress response. Changes in the left/right baseline tympanic membrane temperature (TMT) were used as an indirect ipsilateral indicator of hemisphere activity. Marmosets that were deprived for 3 h had higher cortisol levels than non-deprived controls. Cortisol concentration in the marmosets deprived for 6 h did not differ from controls possibly due to adaptative mechanisms against the detrimental effects of prolonged high cortisol levels. Interestingly, FD stress may have been processed more symmetrically at first, as indicated by the bilateral increase in TMT at the 3 h interval. As the event progressed (i.e., 6 h), a clear rightward TMT bias suggests that hemisphere activity had become asymmetrical. Therefore, the sudden loss of temporal predictability of an entrained routine feeding schedule induces time-dependent changes in the cortisol stress response and shifts in the TMT (and potentially hemisphere activity) lateralization bias of adult captive marmosets.

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Relationship between body temperature, weight, and hematological parameters of black tufted‐ear marmosets (Callithrix penicillata)

Cited by 6 publications

References 32 publications

Rightward Tympanic Membrane Temperature Bias During Acute Restraint-Isolation Stress in Marmoset Monkeys

Rightward Tympanic Membrane Temperature Bias During Acute Restraint-Isolation Stress in Marmoset Monkeys

Oral metformin for type-2 diabetes mellitus treatment in a black-tufted marmoset (Callithrix penicillata)

Time-Dependent Changes in Cortisol and Tympanic Temperature Lateralization During Food Deprivation Stress in Marmoset Monkeys

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