2020
DOI: 10.3892/etm.2020.8961
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Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review)

Abstract: Allergic diseases have been classified in the last decades using various theories. The main classes of the newest classification in allergic respiratory diseases focus on the characterization of the endotype (which takes into account biomarkers related to determinant pathophysiological mechanisms) and of the phenotype (based on the description of the disease). Th2, Th1 and Th17 lymphocytes and the type of inflammatory response mediated by them represent the basis for Th2 and non-Th2 endotype classification. In… Show more

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Cited by 25 publications
(36 citation statements)
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References 121 publications
(148 reference statements)
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“…Correlating allergic rhinitis cases with nasal sinus ultrasound could be a future step in the management of this pathology (13). Thus, we hope that our data will help shift the use of sonography from experimental to clinical practice in ENT and other allied specialties, such as ophthalmology, plastic surgery, and trauma surgery (14,15).…”
Section: Discussionmentioning
confidence: 88%
“…Correlating allergic rhinitis cases with nasal sinus ultrasound could be a future step in the management of this pathology (13). Thus, we hope that our data will help shift the use of sonography from experimental to clinical practice in ENT and other allied specialties, such as ophthalmology, plastic surgery, and trauma surgery (14,15).…”
Section: Discussionmentioning
confidence: 88%
“…Three major allergens have been identified in P. orientalis: Pla or 1, a non-glycosylated protein, and a member of invertase/pectin methylesterase inhibitor family, with a molecular weight of 18 kDa; Pla or 2, a 43 kDa glycoprotein, and a polygalacturonase; and Pla or 3, belonging to non-specific lipid-transfer proteins (ns-LTPs), and a 9-10 kDa protein (12). The IgE-reactive components of P. orientalis pollen described earlier showed a higher level of cross-reactivity with P. occidentalis pollen in comparison with P. acerifolia pollen in an Iranian study (32,36).…”
Section: Platanus Orientalis (Oriental Plane)mentioning
confidence: 90%
“…The diagnostic value of IL-8 levels could be influenced by other diseases in which high levels of IL-8 are found, such as asthma both allergic and non-allergic types, or other common inflammatory diseases, such as viral infections (55).…”
Section: Discussionmentioning
confidence: 99%