Relationship between connectivity indexes of pyrido(1,2a) pyrimidin-4- ones and their liquid–liquid partition data obtained by gas–liquid chromatography

Structure-retention relationship analysis for some mono- and polycyclic aromatic hydrocarbons in reversed-phase liquid chromatography using molecular connectivity

“…1983, 46, 1640-1647. (16) Engelhard!, H.; Ahr, G. Chromatographia 1981, 14, 227-233. (17) Wetherold, R. G.; Wissler, E. H.; Bischoff, K. B. Adv.…”

“…Liquid chromatographic retention on reversed phases (RPLC) is highly dependent upon molecular structure and is the property correlated with molecular connectivity in this paper. Molecular connectivity has been used to predict gas chromatographic (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) and/or liquid chromatographic retention (21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40) for a variety of compounds. This study was undertaken to ascertain whether multivariable expressions of molecular connectivity would improve reported predictions of the RPLC retention of alkylbenzenes and polycyclic aromatic hydrocarbons (hereafter referred to collectively as "hydroaromatics"-compounds containing only carbon and hydrogen and an aromatic site).…”