Relationship between daytime napping and cardiovascular disease: A two-sample mendelian randomization study

Chen, Shi; Hu, Zhenliang; He, Linkang; Bai, Xueke; Li, Haotong; Xu, Xinjie; Hu, Shengshou; Chen, Liang

doi:10.1016/j.hjc.2023.05.005

Cited by 3 publications

(1 citation statement)

References 34 publications

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“…In addition, instead of total sleep duration, most studies evaluate the association between midday-naps or siestas (i.e., day-time naps, usually taken in the early afternoon and/or after the midday meal in the Mediterranean lifestyle) and health [ 41 , 42 , 43 , 44 ]. Daytime naps have shown mixed results in the literature concerning mortality and CVD risk, depending on the reason people have daytime naps; if the reason is for stress-relief, as it was common in the Mediterranean lifestyle, daytime naps might have beneficial effects, but if the reason is to fix inadequate night sleep due to symptoms such as depression or cognitive decline, daytime naps might not suffice to reverse the increased CVD risk associated with these diseases [ 10 , 41 , 42 ]. Thus, future studies on the effect of daytime naps on CVD risk should consider overall sleep habits and either use sleep duration as a covariate or differentiate results by sleep duration.…”

Section: Discussionmentioning

confidence: 99%

Mediterranean Diet and Cardiovascular Disease: The Moderating Role of Adequate Sleep—Results from the ATTICA Cohort Study (2002–2022)

Damigou,

Chrysohoou,

Vafia

et al. 2023

Nutrients

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The relationship between diet, sleep duration and cardiovascular disease (CVD) has not been well understood. The aim of the present study was to test the potential modifying role of sleep duration in the association between adherence to the Mediterranean-type diet (MD) and CVD risk. The study consisted of n = 313 initially free-of-CVD adults, from the ATTICA cohort study (2002–2022), with available information on sleep habits. Sleep habits were categorized as inadequate and adequate sleep duration (< or ≥7 h/day, respectively). In multi-adjusted analysis, MD adherence was inversely associated with CVD risk [Hazard Ratio-HR per 1/55 in MedDietScore: 0.80, 95% Confidence Interval-CI: 0.65, 0.98]. A significant interaction between sleep duration and MedDietScore was observed (p < 0.001). In subgroup analysis, the protective association between MD adherence and CVD risk was found only in participants who slept adequately, i.e., >7 h/day [HR:0.80, 95%CI: 0.65, 0.98]. Those who had a high adherence to the MD along with adequate sleep habits, had a 70% reduced 20-year CVD risk [HR:0.30, 95%CI: 0.11, 0.80], compared to those who had a low MD adherence and inadequate sleep habits. Sleep duration should be a part of an individual’s lifestyle, together with dietary and other habits, to effectively evaluate CVD risk for future events.

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Section: Discussionmentioning

confidence: 99%

Mediterranean Diet and Cardiovascular Disease: The Moderating Role of Adequate Sleep—Results from the ATTICA Cohort Study (2002–2022)

Damigou,

Chrysohoou,

Vafia

et al. 2023

Nutrients

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Long daytime napping: A silent danger for hypertensive individuals

Wu,

Liu,

Huang

et al. 2024

Euro J of Neurology

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Background and purposeHypertension significantly contributes to stroke. Previous research has indicated a connection between daytime napping and stroke. Research on the connection between daytime napping duration and first stroke in hypertensive individuals is lacking nevertheless.MethodsThis research, which ran from 24 August 2013 to 31 December 2022, recruited 11,252 individuals with hypertension and without a history of stroke from the China Stroke Primary Prevention Trial. To determine the relationship between daytime napping duration and stroke onset in hypertensive individuals, we conducted analyses for threshold effects, multivariate‐adjusted Cox proportional hazard regression models, and Kaplan–Meier survival curves.ResultsThe duration of daytime napping (<75 min) was positively correlated with stroke risk; beyond 75 min, the risk did not increase further. When compared to hypertensive individuals who napped for 1–30 min, daytime napping 31–60 min (hazard ratio [HR] = 1.27, 95% confidence interval [CI] = 1.06–1.53) and >60 min (HR = 1.37, 95% CI = 1.14–1.65) were substantially related with a greater risk of first stroke. Additionally, this correlation was absent in cases of hemorrhagic stroke, but present in cases of ischemic stroke, specifically for hypertensive individuals who napped for 31–60 min or >60 min (p < 0.05). Kaplan–Meier survival curves displayed that hypertensive individuals who extended daytime napping had an elevated incidence of stroke.ConclusionsHypertensive individuals who take longer daytime naps (>30 min) are at an elevated risk of stroke onset, particularly ischemic stroke, irrespective of other factors.

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Self‐reported sleep duration and quality and cardiovascular diseases among middle‐aged and older Chinese: A 7‐year longitudinal cohort study

Lv,

Ji,

et al. 2024

J of Clinical Hypertension

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Cardiovascular disease (CVD) is a leading cause of death worldwide, and several studies have attempted to identify its risk factors. This study aimed to investigate the association between sleep duration and sleep quality, and the 7‐year incidence of CVD among middle‐aged and older Chinese individuals. A total of 6682 participants aged 45–90 years from the China Health and Retirement Longitudinal Study database were included in this study. The authors estimated sleep duration and quality based on self‐reported data of night sleep hours and disturbance symptoms, and examined the associations between them and the composite outcome of CVD using logistic regression models. A total of 1692 participants (25.32%) reported new CVD events during follow‐up. Short sleep duration (< 6 h/night) was significantly associated with a higher risk of CVD in all three models (p < .05). However, this was not observed for long sleep duration (> 8 h/night). Additionally, participants with mild sleep disturbance in all three models, and severe sleep disturbance in Models 2 and 3 had a significantly higher risk of CVD (p < .05). After stratification by age and daytime napping, we still found a significant association between short sleep duration and CVD in individuals aged 45–59 years, and between sleep disturbance and CVD in non‐nappers (p < .05). However, these associations were not significant in individuals aged ≥60 years or in nappers (p > .05). In conclusion, short sleep duration and sleep disturbance are both associated with an increased risk of CVD in middle‐aged and older Chinese individuals.

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Relationship between daytime napping and cardiovascular disease: A two-sample mendelian randomization study

Cited by 3 publications

References 34 publications

Mediterranean Diet and Cardiovascular Disease: The Moderating Role of Adequate Sleep—Results from the ATTICA Cohort Study (2002–2022)

Mediterranean Diet and Cardiovascular Disease: The Moderating Role of Adequate Sleep—Results from the ATTICA Cohort Study (2002–2022)

Long daytime napping: A silent danger for hypertensive individuals

Self‐reported sleep duration and quality and cardiovascular diseases among middle‐aged and older Chinese: A 7‐year longitudinal cohort study

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