Relationship between depressive symptoms and adherence to direct-acting antivirals: Implications for Hepatitis C treatment among people who inject drugs on medications for opioid use disorder

Pericot‐Valverde, Irene; Heo, Moonseong; Niu, Jiajing; Rennert, Lior; Norton, Brianna L.; Akiyama, Matthew J.; Arnsten, Julia H.; Litwin, Alain H.

doi:10.1016/j.drugalcdep.2022.109403

Cited by 4 publications

(3 citation statements)

References 44 publications

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“…Secondly, since the number of patients who could reach the antiviral treatment is low, there were not enough samples to assess the re-infection rates of the patients. Difficulties in patients' access to antiviral treatment may also be related to some other major psychiatric problems (29,30). There was lack of data whether patients had major depressive disorder, anxiety disorder or personality disorder.…”

Section: Discussionmentioning

confidence: 99%

Effects of Recent IV Drug Use and Severity of Psychiatric Symptoms to Antiviral Treatment in People Who Inject Drugs

KARABULUT¹

2023

Bağımlılık Dergisi

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Objective: People who inject drugs have major contribution to a rise in hepatitis C virus (HCV) infections. Despite efficacy and safety of direct-acting antiviral (DAA) therapies, patients may have difficulties to receive treatment. In this study we aimed to examine the effect of clinical variables in substance users to access to antiviral treatment and the treatment rate. Method: In this retrospective study, we examined the files of 5586 patients who admitted to Outpatient Treatment Center (OTC) between July 2020-April 2021 and files of 121 patients with positive Anti-HCV results were included. All patients had been routinely assessed by Addiction Profile Index (API) and Adult Attention Deficit Hyperactivity Disorder Self-Rating Scale (ASRS).. Results: Of 121 patients, the most used substance was opiate. Because of the insurance restrictions, DAA treatment might be prescribed in only tertiary referral hospitals. All patients had been referred to a tertiary referral hospital. The mean duration from Anti-HCV testing to treatment was 190.3 days. Actively iv substance users were more likely to use substances every day ( 81.5 % vs 41.5%), start using the current substance at younger age (19.1 vs 20.9), have higher total API scores, have higher depression (4.7 vs 3.7), anxiety subscale scores, and ASRS-A scores (11.3 vs 8.3). Actively iv substance users were no more likely to have longer Anti-HCV – treatment duration (100.4 ve 254.5) and have worse treatment completion rates (% 100 vs 67.7). Conclusion: According to research findings, young adults' expectations to obtain social status and social conformity through the acquisition of a product may affect spending time for online shopping and they may lose control of the use of credit cards.

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Section: Discussionmentioning

confidence: 99%

Effects of Recent IV Drug Use and Severity of Psychiatric Symptoms to Antiviral Treatment in People Who Inject Drugs

KARABULUT¹

2023

Bağımlılık Dergisi

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“…The use of telehealth to expand hepatitis care in Australia was to ensure greater monitoring of treatment, 53 in Mexico for economic factors 54 and in Spain to ensure access to specialists in the population deprived of freedom. 55 In the symbolic dimension, it should be noted that adherence to hepatitis treatment is related to the ethnic group's cultural baggage and beliefs, 56 as well as to the population's mental health problems, medication abuse, and alcohol consumption, 57 in addition to the user's level of knowledge and interaction with the health care professional. 58 The Covid-19 pandemic made it possible to expose with greater emphasis the need to organize the HCN to meet social needs with greater resoluteness.…”

Section: People With Hepatitis In Healthcare Servicesmentioning

confidence: 99%

Aspects that weaken access of people with viral hepatitis to healthcare services

Gleriano

Chaves

2023

Esc. Anna Nery

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Objective to analyze the aspects that weaken the access to viral hepatitis care. Method evaluative research, developed in the State of Mato Grosso, with managers of the State Health Department and professionals from reference services. For data collection, interviews were conducted. Content analysis was used in a theme-based approach and, for the discussion, the dimensions of the analysis model of universal access to health services. Results The political dimension presents little participation of federal and state management in the proposition of guidelines, coordination, and pacts. In the economic-social dimension, the low investment in the public network and the difficulty in hiring specialist professionals were identified. In the organizational dimension, the regulation of access, assistance, and the logistics of treatment suffers from geographic barriers, besides the low use of monitoring and evaluation. In the technical dimension, the little professional training and the absence of a shared network project were noticed. In the symbolic dimension, cultural factors, beliefs, values, and subjectivity interfere with access. Conclusion and implications for the practice the results collaborate to direct confrontation actions, aiming to reach the goals agreed upon for the 2030 Agenda

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“…Gleriano JS, Chaves LDP cultural e de crenças de grupo étnico, 56 além de população com os problemas de saúde mental, o uso abusivo de medicamentos, o consumo de álcool, 57 além do nível de conhecimento que o usuário possui e a interação dele com o profissional de saúde. 58 A pandemia da Covid-19 possibilitou expor com maior ênfase a necessidade de organização da RAS para atender com maior resolubilidade às necessidades sociais.…”

Section: Pessoas Com Hepatites Em Serviços De Saúdeunclassified

Aspectos que fragilizam o acesso das pessoas com hepatites virais aos serviços de saúde

Gleriano

Chaves

2023

Esc. Anna Nery

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Resumo Objetivo analisar os aspectos que fragilizam o acesso à atenção às hepatites virais. Método pesquisa avaliativa, desenvolvida no Estado de Mato Grosso, com os gestores da Secretaria de Estado de Saúde e os profissionais dos serviços de referência. Para a coleta de dados realizaram-se entrevistas, utilizou-se a Análise de Conteúdo, na vertente temática e, para a discussão as dimensões do modelo de análise de acesso universal aos serviços de saúde. Resultados a dimensão política apresenta pouca participação da gestão federal e estadual na proposição de diretrizes, coordenação e pactuação. Na dimensão econômico-social o baixo investimento na rede pública e a dificuldade de fixação de profissionais especialistas. Na dimensão organizacional a regulação do acesso, da assistência e a logística do tratamento sofrem com as barreiras geográficas, além do baixo uso do monitoramento e a avaliação. Na dimensão técnica a pouca formação profissional e a ausência de projeto compartilhado em rede. Na dimensão simbólica os fatores culturais, de crença, valores e subjetividade interferem no acesso. Conclusão e implicações para a prática os resultados colaboram para direcionar ações de enfrentamento, almejando alcançar as metas pactuadas para a Agenda 2030.

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Relationship between depressive symptoms and adherence to direct-acting antivirals: Implications for Hepatitis C treatment among people who inject drugs on medications for opioid use disorder

Cited by 4 publications

References 44 publications

Effects of Recent IV Drug Use and Severity of Psychiatric Symptoms to Antiviral Treatment in People Who Inject Drugs

Effects of Recent IV Drug Use and Severity of Psychiatric Symptoms to Antiviral Treatment in People Who Inject Drugs

Aspects that weaken access of people with viral hepatitis to healthcare services

Aspectos que fragilizam o acesso das pessoas com hepatites virais aos serviços de saúde

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