Relationship between diabetic neuropathic pain and comorbidity. Their impact on pain intensity, diabetes complications and quality of life in patients with type-2 diabetes mellitus

Naranjo, Cristina; Ortega-Jiménez, Patricia; Reguero, Leticia del; Moratalla, Guillermo; Failde, Inmaculada

doi:10.1016/j.diabres.2020.108236

Cited by 29 publications

(29 citation statements)

References 37 publications

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“…Os resultados da pesquisa desenvolvida em Teresina foram semelhantes. 25 Neste estudo, quase a totalidade dos pacientes referiram dor, sendo a maioria com presença de dor em pés ou panturrilhas. Alguns pesquisadores asseguram que um a cada cinco indivíduos com DM têm dor neuropática.…”

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“…5,10 Em outros estudos para avaliação da neuropatia dolorosa, os descritores mais comuns são queimação, formigamento ou dormência. 19,[25][26][27] Além disso, alguns pacientes também descrevem desequilíbrio, quedas, choques, picadas, agulhadas, bem como desconforto ou dor ao toque de lençóis e cobertores e piora em repouso. 5 Nesta investigação, a dor moderada e intensa foi prevalente entre os grupos.…”

Section: Disc Disc Disc Discussão Ussão Ussão Ussãounclassified

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Comparação da dor e qualidade de vida entre indivíduos com e sem neuropatia diabética

et al. 2021

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Objetivo:comparar a dor e a qualidade de vida de indivíduos com e sem neuropatia diabética. Método: estudo transversal realizado com 251 participantes com diabetes mellitus tipo 2. Utilizou-se a escala Leeds Assessment of Neuropathic Symptoms and Signs (LANSS)para avaliar neuropatia diabética, características da dor, perda de sensibilidade protetora (PSP) e avaliar a qualidade de vidapelo Short-Form 6 Dimensions-Brasil/SF-6D. Realizou-se análise estatística descritiva. Resultados:16,3% apresentaram neuropatia, 97,6% queixaram-se de dor, sendo a maioria crônica e nos pés ou panturrilhas. 51,2% dos neuropáticos tiveram PSP no teste do monofilamento (p=0,001). Os descritores de dor mais referidos pelos neuropáticos: queimação (p=0,004), formigamento (p=0,002) e alfinetada e/ou agulhada (p=0,003) e os domínios de qualidade de vida afetados foram: dor, saúde mental e vitalidade. Conclusão:aqueles com neuropatia têm maior intensidade de dor, acordam à noite e apresentam alteração na sensibilidade dos pés, que pode ser rastreada na atenção primária.

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Comparação da dor e qualidade de vida entre indivíduos com e sem neuropatia diabética

et al. 2021

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“…There is a notable evidence base that discusses the interference on physical and psychological functioning of neuropathic pain in the context and out of the context of diabetes [12,13]. Indeed, mental comorbidity and sleep disorders are factors associated with pDN and greater pain intensity, more diabetes complications and lower quality of life [14]. It is not uncommon to assess patients in a tertiary centre and discover comorbid psychological distress.…”

Section: Psychosocial Impact In Diabetic Neuropathymentioning

confidence: 99%

A Consideration of the Psychological Aspects to Managing Patients with Painful Diabetic Neuropathy: An Insight into Pain Management Services at a Tertiary Centre in the UK

2020

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Painful diabetic neuropathy (pDN) is characterised by both sensory and affective disturbances, suggesting a complex bidirectional relationship of neuropathic pain and mood disorders. Data on pDN indicate that neuropathic pain reduces quality of life, including mood and physical and social functioning. Depression and pain coping strategies such as catastrophising and social support predict pain severity. There is a significant and reciprocal relationship between depressed mood and increased pain. The key features of assessing people with neuropathic pain in relation to psychological aspects of their health are discussed in the context of management in a tertiary pain management centre (The Walton Centre, Liverpool, UK) including cognitive behavioural interventions amongst others to improve the quality of life in patients with pDN. We consider psychological issues as a factor influencing treatment and outcome in patients with pDN.

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“…Type 2 diabetes mellitus (T2DM) is characterized by multivariate systemic complications that significantly impair the quality of life of patients and reduce their life expectancy [1].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus and Associated Obesity and Ways of Its Correction

et al. 2021

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The aim: To analyze and calculate CVR in patients with T2DM and concomitant obesity. Materials and methods: The selection of patients was carried out based on the Uzhhorod District Clinical Hospital, in the period from November 2016 to January 2020. All patients were divided into 3 groups: 1 (n=93) with T2DM and concomitant obesity, 2 (n=87) with T2DM, 3 (n=39) with obesity. The treatment period lasted 1 year and included dosed exercise for at least 30 minutes per day and dietary recommendations. Patients in groups 1 and 2 received metformin 850 mg twice daily in combination with dapagliflozin 10 mg once daily. CVR was determined at the time of enrollment and after 1 year of treatment using: American College of Cardiology / American Heart Association Guideline on the Assessment of Cardiovascular Risk (2013) (ASCVD Risk) and Framingham Risk Score (FRS). Results: The data obtained as a result of the study revealed the highest CVR in patients of group 1, in contrast to group 2 and 3 (p<0.05). After 1 year of complex treatment, CVR indicators were statistically significantly reduced in all experimental groups (p<0.05). Conclusions: Determining CVR parameters and exposure to them within 10 years can remove unwanted cardiovascular complications.

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Relationship between diabetic neuropathic pain and comorbidity. Their impact on pain intensity, diabetes complications and quality of life in patients with type-2 diabetes mellitus

Cited by 29 publications

References 37 publications

Comparação da dor e qualidade de vida entre indivíduos com e sem neuropatia diabética

Comparação da dor e qualidade de vida entre indivíduos com e sem neuropatia diabética

A Consideration of the Psychological Aspects to Managing Patients with Painful Diabetic Neuropathy: An Insight into Pain Management Services at a Tertiary Centre in the UK

Assessment of Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus and Associated Obesity and Ways of Its Correction

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